Johnson IT - Search Results

1

Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer.

Belshaw NJ, Elliott GO, Williams EA, Bradburn DM, Mills SJ, Mathers JC, Johnson IT. Belshaw NJ, et al. Among authors: johnson it. Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1495-501. Cancer Epidemiol Biomarkers Prev. 2004. PMID: 15342451

2

Quantitative profiling of CpG island methylation in human stool for colorectal cancer detection.

Elliott GO, Johnson IT, Scarll J, Dainty J, Williams EA, Garg D, Coupe A, Bradburn DM, Mathers JC, Belshaw NJ. Elliott GO, et al. Among authors: johnson it. Int J Colorectal Dis. 2013 Jan;28(1):35-42. doi: 10.1007/s00384-012-1532-5. Epub 2012 Jul 13. Int J Colorectal Dis. 2013. PMID: 22791128 Clinical Trial.

3

Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa.

Tapp HS, Commane DM, Bradburn DM, Arasaradnam R, Mathers JC, Johnson IT, Belshaw NJ. Tapp HS, et al. Among authors: johnson it. Aging Cell. 2013 Feb;12(1):148-55. doi: 10.1111/acel.12030. Epub 2012 Dec 6. Aging Cell. 2013. PMID: 23157586 Free PMC article.

4

The effect of diet on the intestinal epigenome.

Johnson IT, Belshaw NJ. Johnson IT, et al. Epigenomics. 2014 Apr;6(2):239-51. doi: 10.2217/epi.14.8. Epigenomics. 2014. PMID: 24811792 Review.

5

Proteomic analysis reveals field-wide changes in protein expression in the morphologically normal mucosa of patients with colorectal neoplasia.

Polley AC, Mulholland F, Pin C, Williams EA, Bradburn DM, Mills SJ, Mathers JC, Johnson IT. Polley AC, et al. Among authors: johnson it. Cancer Res. 2006 Jul 1;66(13):6553-62. doi: 10.1158/0008-5472.CAN-06-0534. Cancer Res. 2006. PMID: 16818627

6

Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia.

Johnson IT, Belshaw NJ. Johnson IT, et al. Food Chem Toxicol. 2008 Apr;46(4):1346-59. doi: 10.1016/j.fct.2007.09.101. Epub 2007 Sep 26. Food Chem Toxicol. 2008. PMID: 17976883 Review.

7

Methylation of the ESR1 CpG island in the colorectal mucosa is an 'all or nothing' process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse.

Belshaw NJ, Elliott GO, Williams EA, Mathers JC, Buckley L, Bahari B, Johnson IT. Belshaw NJ, et al. Among authors: johnson it. Biochem Soc Trans. 2005 Aug;33(Pt 4):709-11. doi: 10.1042/BST0330709. Biochem Soc Trans. 2005. PMID: 16042580

8

Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa.

Belshaw NJ, Elliott GO, Foxall RJ, Dainty JR, Pal N, Coupe A, Garg D, Bradburn DM, Mathers JC, Johnson IT. Belshaw NJ, et al. Among authors: johnson it. Br J Cancer. 2008 Jul 8;99(1):136-42. doi: 10.1038/sj.bjc.6604432. Epub 2008 Jun 10. Br J Cancer. 2008. PMID: 18542073 Free PMC article.

9

Supra-physiological folic acid concentrations induce aberrant DNA methylation in normal human cells in vitro.

Charles MA, Johnson IT, Belshaw NJ. Charles MA, et al. Among authors: johnson it. Epigenetics. 2012 Jul;7(7):689-94. doi: 10.4161/epi.20461. Epub 2012 Jul 1. Epigenetics. 2012. PMID: 22617627 Free article.

10

Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa.

Belshaw NJ, Pal N, Tapp HS, Dainty JR, Lewis MP, Williams MR, Lund EK, Johnson IT. Belshaw NJ, et al. Among authors: johnson it. Carcinogenesis. 2010 Jun;31(6):1158-63. doi: 10.1093/carcin/bgq077. Epub 2010 Apr 15. Carcinogenesis. 2010. PMID: 20395289

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