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Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure.
Daiber A, Oelze M, Coldewey M, Kaiser K, Huth C, Schildknecht S, Bachschmid M, Nazirisadeh Y, Ullrich V, Mülsch A, Münzel T, Tsilimingas N. Daiber A, et al. Among authors: bachschmid m. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1865-74. doi: 10.1016/j.bbrc.2005.10.106. Epub 2005 Nov 11. Biochem Biophys Res Commun. 2005. PMID: 16289107
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction.
Wenzel P, Schuhmacher S, Kienhöfer J, Müller J, Hortmann M, Oelze M, Schulz E, Treiber N, Kawamoto T, Scharffetter-Kochanek K, Münzel T, Bürkle A, Bachschmid MM, Daiber A. Wenzel P, et al. Among authors: bachschmid mm. Cardiovasc Res. 2008 Nov 1;80(2):280-9. doi: 10.1093/cvr/cvn182. Epub 2008 Jul 2. Cardiovasc Res. 2008. PMID: 18596060 Free PMC article.
Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity. Implications for mitochondrial oxidative stress and nitrate tolerance.
Wenzel P, Hink U, Oelze M, Schuppan S, Schaeuble K, Schildknecht S, Ho KK, Weiner H, Bachschmid M, Münzel T, Daiber A. Wenzel P, et al. Among authors: bachschmid m. J Biol Chem. 2007 Jan 5;282(1):792-9. doi: 10.1074/jbc.M606477200. Epub 2006 Nov 13. J Biol Chem. 2007. PMID: 17102135 Free article.
Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging.
Oelze M, Kröller-Schön S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Münzel T, Daiber A. Oelze M, et al. Among authors: bachschmid m. Hypertension. 2014 Feb;63(2):390-6. doi: 10.1161/HYPERTENSIONAHA.113.01602. Epub 2013 Dec 2. Hypertension. 2014. PMID: 24296279
Ebselen as a peroxynitrite scavenger in vitro and ex vivo.
Daiber A, Zou MH, Bachschmid M, Ullrich V. Daiber A, et al. Among authors: bachschmid m. Biochem Pharmacol. 2000 Jan 15;59(2):153-60. doi: 10.1016/s0006-2952(99)00309-3. Biochem Pharmacol. 2000. PMID: 10810449
98 results