Lu Y - Search Results

1

A novel cyclic enkephalin analogue with potent opioid antagonist activity.

Weltrowska G, Lu Y, Lemieux C, Chung NN, Schiller PW. Weltrowska G, et al. Among authors: lu y. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4731-3. doi: 10.1016/j.bmcl.2004.06.077. Bioorg Med Chem Lett. 2004. PMID: 15324897

2

Conversion of delta-, kappa- and mu-receptor selective opioid peptide agonists into delta-, kappa- and mu-selective antagonists.

Schiller PW, Weltrowska G, Nguyen TM, Lemieux C, Chung NN, Lu Y. Schiller PW, et al. Among authors: lu y. Life Sci. 2003 Jun 27;73(6):691-8. doi: 10.1016/s0024-3205(03)00389-8. Life Sci. 2003. PMID: 12801590

3

Replacement of the N-terminal tyrosine residue in opioid peptides with 3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid (Dcp) results in novel opioid antagonists.

Lu Y, Lum TK, Leow Augustine YW, Weltrowska G, Nguyen TM, Lemieux C, Chung NN, Schiller PW. Lu Y, et al. J Med Chem. 2006 Aug 24;49(17):5382-5. doi: 10.1021/jm060369k. J Med Chem. 2006. PMID: 16913729

4

Novel opioid peptide derived antagonists containing (2S)-2-methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid [(2S)-Mdcp].

Ghosh A, Luo J, Liu C, Weltrowska G, Lemieux C, Chung NN, Lu Y, Schiller PW. Ghosh A, et al. Among authors: lu y. J Med Chem. 2008 Sep 25;51(18):5866-70. doi: 10.1021/jm8004702. J Med Chem. 2008. PMID: 18800771 Free PMC article.

5

"Carba"-analogues of fentanyl are opioid receptor agonists.

Weltrowska G, Chung NN, Lemieux C, Guo J, Lu Y, Wilkes BC, Schiller PW. Weltrowska G, et al. Among authors: lu y. J Med Chem. 2010 Apr 8;53(7):2875-81. doi: 10.1021/jm9019068. J Med Chem. 2010. PMID: 20218625 Free PMC article.

6

L-threonine-derived novel bifunctional phosphine-sulfonamide catalyst-promoted enantioselective aza-Morita-Baylis-Hillman reaction.

Zhong F, Wang Y, Han X, Huang KW, Lu Y. Zhong F, et al. Among authors: lu y. Org Lett. 2011 Mar 18;13(6):1310-3. doi: 10.1021/ol103145g. Epub 2011 Feb 18. Org Lett. 2011. PMID: 21332151

7

Organocatalytic Michael addition of aldehydes to vinyl sulfones: enantioselective alpha-alkylations of aldehydes and their derivatives.

Zhu Q, Lu Y. Zhu Q, et al. Among authors: lu y. Org Lett. 2008 Nov 6;10(21):4803-6. doi: 10.1021/ol8019296. Epub 2008 Oct 4. Org Lett. 2008. PMID: 18834133

8

Asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones via bifunctional thiourea-mediated intramolecular cyclization.

Liu X, Lu Y. Liu X, et al. Among authors: lu y. Org Lett. 2010 Dec 3;12(23):5592-5. doi: 10.1021/ol102519z. Epub 2010 Nov 3. Org Lett. 2010. PMID: 21047098

9

Enantioselective conjugate addition of nitroalkanes to vinyl sulfone: an organocatalytic access to chiral amines.

Zhu Q, Lu Y. Zhu Q, et al. Among authors: lu y. Org Lett. 2009 Apr 16;11(8):1721-4. doi: 10.1021/ol9003349. Org Lett. 2009. PMID: 19317479

10

Novel synthetic luteolin analogue-caused sensitization of tumor necrosis factor-alpha-induced apoptosis in human tumor cells.

Cheng L, Tan H, Wu X, Hu R, Aw C, Zhao M, Shen HM, Lu Y. Cheng L, et al. Among authors: lu y. Org Biomol Chem. 2008 Nov 21;6(22):4102-4. doi: 10.1039/b813904k. Epub 2008 Oct 9. Org Biomol Chem. 2008. PMID: 18972039

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