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7,010 results

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Page 1
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: metabolism-directed optimization studies towards orally bioavailable derivatives.
Vergne F, Bernardelli P, Lorthiois E, Pham N, Proust E, Oliveira C, Mafroud AK, Ducrot P, Wrigglesworth R, Berlioz-Seux F, Coleon F, Chevalier E, Moreau F, Idrissi M, Tertre A, Descours A, Berna P, Li M. Vergne F, et al. Among authors: oliveira c. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4615-21. doi: 10.1016/j.bmcl.2004.07.009. Bioorg Med Chem Lett. 2004. PMID: 15324875
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
Vergne F, Bernardelli P, Lorthiois E, Pham N, Proust E, Oliveira C, Mafroud AK, Royer F, Wrigglesworth R, Schellhaas J, Barvian M, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Berna P, Soulard P. Vergne F, et al. Among authors: oliveira c. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4607-13. doi: 10.1016/j.bmcl.2004.07.008. Bioorg Med Chem Lett. 2004. PMID: 15324874
Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
Lorthiois E, Bernardelli P, Vergne F, Oliveira C, Mafroud AK, Proust E, Heuze L, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Wrigglesworth R, Descours A, Soulard P, Berna P. Lorthiois E, et al. Among authors: oliveira c. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4623-6. doi: 10.1016/j.bmcl.2004.07.011. Bioorg Med Chem Lett. 2004. PMID: 15324876
Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
Bernardelli P, Lorthiois E, Vergne F, Oliveira C, Mafroud AK, Proust E, Pham N, Ducrot P, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Chevalier E, Descours A, Berlioz-Seux F, Berna P, Li M. Bernardelli P, et al. Among authors: oliveira c. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4627-31. doi: 10.1016/j.bmcl.2004.07.010. Bioorg Med Chem Lett. 2004. PMID: 15324877
From triclosan toward the clinic: discovery of nonbiocidal, potent FabI inhibitors for the treatment of resistant bacteria.
Gerusz V, Denis A, Faivre F, Bonvin Y, Oxoby M, Briet S, LeFralliec G, Oliveira C, Desroy N, Raymond C, Peltier L, Moreau F, Escaich S, Vongsouthi V, Floquet S, Drocourt E, Walton A, Prouvensier L, Saccomani M, Durant L, Genevard JM, Sam-Sambo V, Soulama-Mouze C. Gerusz V, et al. Among authors: oliveira c. J Med Chem. 2012 Nov 26;55(22):9914-28. doi: 10.1021/jm301113w. Epub 2012 Oct 23. J Med Chem. 2012. PMID: 23092194
Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence.
Desroy N, Denis A, Oliveira C, Atamanyuk D, Briet S, Faivre F, LeFralliec G, Bonvin Y, Oxoby M, Escaich S, Floquet S, Drocourt E, Vongsouthi V, Durant L, Moreau F, Verhey TB, Lee TW, Junop MS, Gerusz V. Desroy N, et al. Among authors: oliveira c. J Med Chem. 2013 Feb 28;56(4):1418-30. doi: 10.1021/jm301499r. Epub 2013 Feb 14. J Med Chem. 2013. PMID: 23409840
Structural-functional studies of Burkholderia cenocepacia D-glycero-β-D-manno-heptose 7-phosphate kinase (HldA) and characterization of inhibitors with antibiotic adjuvant and antivirulence properties.
Lee TW, Verhey TB, Antiperovitch PA, Atamanyuk D, Desroy N, Oliveira C, Denis A, Gerusz V, Drocourt E, Loutet SA, Hamad MA, Stanetty C, Andres SN, Sugiman-Marangos S, Kosma P, Valvano MA, Moreau F, Junop MS. Lee TW, et al. Among authors: oliveira c. J Med Chem. 2013 Feb 28;56(4):1405-17. doi: 10.1021/jm301483h. Epub 2013 Jan 22. J Med Chem. 2013. PMID: 23256532 Free PMC article.
Nutritional and technological potential of umbu-caja and soursop co-product flours.
Lana VS, Estevam PN, de Castro TB, de São José VPB, Brito-Oliveira TC, Santos PH, Oliveira CAS, Corrêa CB, Rostagno MA, Martino HSD, de Carvalho IMM. Lana VS, et al. Among authors: oliveira cas. Food Res Int. 2025 Jan;200:115520. doi: 10.1016/j.foodres.2024.115520. Epub 2024 Dec 18. Food Res Int. 2025. PMID: 39779150
7,010 results