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Phase II study of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C alpha, in patients with previously treated low-grade non-Hodgkin's lymphoma.
Rao S, Watkins D, Cunningham D, Dunlop D, Johnson P, Selby P, Hancock BW, Fegan C, Culligan D, Schey S, Morris TC, Lissitchkov T, Oliver JW, Holmlund JT. Rao S, et al. Among authors: holmlund jt. Ann Oncol. 2004 Sep;15(9):1413-8. doi: 10.1093/annonc/mdh359. Ann Oncol. 2004. PMID: 15319248 Free article. Clinical Trial.
A phase I/II study of LY900003, an antisense inhibitor of protein kinase C-alpha, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.
Villalona-Calero MA, Ritch P, Figueroa JA, Otterson GA, Belt R, Dow E, George S, Leonardo J, McCachren S, Miller GL, Modiano M, Valdivieso M, Geary R, Oliver JW, Holmlund J. Villalona-Calero MA, et al. Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6086-93. doi: 10.1158/1078-0432.CCR-04-0779. Clin Cancer Res. 2004. PMID: 15447994 Clinical Trial.
Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-alpha delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas.
Grossman SA, Alavi JB, Supko JG, Carson KA, Priet R, Dorr FA, Grundy JS, Holmlund JT. Grossman SA, et al. Among authors: holmlund jt. Neuro Oncol. 2005 Jan;7(1):32-40. doi: 10.1215/S1152851703000353. Neuro Oncol. 2005. PMID: 15701280 Free PMC article. Clinical Trial.
45 results