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Nitric oxide-releasing NSAIDs inhibit interleukin-1beta converting enzyme-like cysteine proteases and protect endothelial cells from apoptosis induced by TNFalpha.
Fiorucci S, Santucci L, Federici B, Antonelli E, Distrutti E, Morelli O, Renzo GD, Coata G, Cirino G, Soldato PD, Morelli A. Fiorucci S, et al. Among authors: soldato pd. Aliment Pharmacol Ther. 1999 Mar;13(3):421-35. doi: 10.1046/j.1365-2036.1999.00442.x. Aliment Pharmacol Ther. 1999. PMID: 10102977
New prostaglandin derivative for glaucoma treatment.
Perrino E, Uliva C, Lanzi C, Soldato PD, Masini E, Sparatore A. Perrino E, et al. Among authors: soldato pd. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1639-42. doi: 10.1016/j.bmcl.2009.02.007. Epub 2009 Feb 8. Bioorg Med Chem Lett. 2009. PMID: 19233645