Anderson JJ - Search Results

1

The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety.

Busse CS, Brodkin J, Tattersall D, Anderson JJ, Warren N, Tehrani L, Bristow LJ, Varney MA, Cosford ND. Busse CS, et al. Among authors: anderson jj. Neuropsychopharmacology. 2004 Nov;29(11):1971-9. doi: 10.1038/sj.npp.1300540. Neuropsychopharmacology. 2004. PMID: 15305166

2

Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.

Chua PC, Nagasawa JY, Bleicher LS, Munoz B, Schweiger EJ, Tehrani L, Anderson JJ, Cramer M, Chung J, Green MD, King CD, Reyes-Manalo G, Cosford ND. Chua PC, et al. Among authors: anderson jj. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4589-93. doi: 10.1016/j.bmcl.2005.06.099. Bioorg Med Chem Lett. 2005. PMID: 16115767

3

Metabotropic glutamate receptor mGlu5 is a mediator of appetite and energy balance in rats and mice.

Bradbury MJ, Campbell U, Giracello D, Chapman D, King C, Tehrani L, Cosford ND, Anderson J, Varney MA, Strack AM. Bradbury MJ, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):395-402. doi: 10.1124/jpet.104.076406. Epub 2004 Dec 8. J Pharmacol Exp Ther. 2005. PMID: 15590770

4

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity.

Cosford ND, Tehrani L, Roppe J, Schweiger E, Smith ND, Anderson J, Bristow L, Brodkin J, Jiang X, McDonald I, Rao S, Washburn M, Varney MA. Cosford ND, et al. J Med Chem. 2003 Jan 16;46(2):204-6. doi: 10.1021/jm025570j. J Med Chem. 2003. PMID: 12519057

5

[3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization.

Anderson JJ, Rao SP, Rowe B, Giracello DR, Holtz G, Chapman DF, Tehrani L, Bradbury MJ, Cosford ND, Varney MA. Anderson JJ, et al. J Pharmacol Exp Ther. 2002 Dec;303(3):1044-51. doi: 10.1124/jpet.102.040618. J Pharmacol Exp Ther. 2002. PMID: 12438526

6

Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge.

Lorrain DS, Schaffhauser H, Campbell UC, Baccei CS, Correa LD, Rowe B, Rodriguez DE, Anderson JJ, Varney MA, Pinkerton AB, Vernier JM, Bristow LJ. Lorrain DS, et al. Among authors: anderson jj. Neuropsychopharmacology. 2003 Sep;28(9):1622-32. doi: 10.1038/sj.npp.1300238. Epub 2003 Jun 25. Neuropsychopharmacology. 2003. PMID: 12825094

7

In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

Anderson JJ, Bradbury MJ, Giracello DR, Chapman DF, Holtz G, Roppe J, King C, Cosford ND, Varney MA. Anderson JJ, et al. Eur J Pharmacol. 2003 Jul 18;473(1):35-40. doi: 10.1016/s0014-2999(03)01935-6. Eur J Pharmacol. 2003. PMID: 12877935

8

5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity.

Roppe JR, Wang B, Huang D, Tehrani L, Kamenecka T, Schweiger EJ, Anderson JJ, Brodkin J, Jiang X, Cramer M, Chung J, Reyes-Manalo G, Munoz B, Cosford ND. Roppe JR, et al. Among authors: anderson jj. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3993-6. doi: 10.1016/j.bmcl.2004.05.037. Bioorg Med Chem Lett. 2004. PMID: 15225713

9

Role of metabotropic glutamate receptor subtype 5 (mGluR5) in the maintenance of cold hypersensitivity following a peripheral mononeuropathy in the rat.

Urban MO, Hama AT, Bradbury M, Anderson J, Varney MA, Bristow L. Urban MO, et al. Neuropharmacology. 2003 Jun;44(8):983-93. doi: 10.1016/s0028-3908(03)00118-7. Neuropharmacology. 2003. PMID: 12763091

10

Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268.

Lorrain DS, Baccei CS, Bristow LJ, Anderson JJ, Varney MA. Lorrain DS, et al. Among authors: anderson jj. Neuroscience. 2003;117(3):697-706. doi: 10.1016/s0306-4522(02)00652-8. Neuroscience. 2003. PMID: 12617973

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