Smith AJ - Search Results

1

Multiple structural features of steroids mediate subtype-selective effects on human alpha4beta3delta GABAA receptors.

Pillai GV, Smith AJ, Hunt PA, Simpson PB. Pillai GV, et al. Among authors: smith aj. Biochem Pharmacol. 2004 Sep 1;68(5):819-31. doi: 10.1016/j.bcp.2004.05.013. Biochem Pharmacol. 2004. PMID: 15294445

2

Methodological approaches for the study of GABA(A) receptor pharmacology and functional responses.

Smith AJ, Simpson PB. Smith AJ, et al. Anal Bioanal Chem. 2003 Nov;377(5):843-51. doi: 10.1007/s00216-003-2172-y. Epub 2003 Aug 23. Anal Bioanal Chem. 2003. PMID: 12937886 Review.

3

Compounds exhibiting selective efficacy for different beta subunits of human recombinant gamma-aminobutyric acid A receptors.

Smith AJ, Oxley B, Malpas S, Pillai GV, Simpson PB. Smith AJ, et al. J Pharmacol Exp Ther. 2004 Nov;311(2):601-9. doi: 10.1124/jpet.104.070342. Epub 2004 Jun 21. J Pharmacol Exp Ther. 2004. PMID: 15210837

4

Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors.

Thompson SA, Wheat L, Brown NA, Wingrove PB, Pillai GV, Whiting PJ, Adkins C, Woodward CH, Smith AJ, Simpson PB, Collins I, Wafford KA. Thompson SA, et al. Among authors: smith aj. Br J Pharmacol. 2004 May;142(1):97-106. doi: 10.1038/sj.bjp.0705689. Epub 2004 Apr 20. Br J Pharmacol. 2004. PMID: 15100159 Free PMC article.

5

An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

Dawson GR, Maubach KA, Collinson N, Cobain M, Everitt BJ, MacLeod AM, Choudhury HI, McDonald LM, Pillai G, Rycroft W, Smith AJ, Sternfeld F, Tattersall FD, Wafford KA, Reynolds DS, Seabrook GR, Atack JR. Dawson GR, et al. Among authors: smith aj. J Pharmacol Exp Ther. 2006 Mar;316(3):1335-45. doi: 10.1124/jpet.105.092320. Epub 2005 Dec 2. J Pharmacol Exp Ther. 2006. PMID: 16326923

6

Characterisation of a sphingosine 1-phosphate-activated Ca2+ signalling pathway in human neuroblastoma cells.

Villullas IR, Smith AJ, Heavens RP, Simpson PB. Villullas IR, et al. Among authors: smith aj. J Neurosci Res. 2003 Jul 15;73(2):215-26. doi: 10.1002/jnr.10636. J Neurosci Res. 2003. PMID: 12836164

7

Sarcosine based indandione hGlyT1 inhibitors.

Thomson CG, Duncan K, Fletcher SR, Huscroft IT, Pillai G, Raubo P, Smith AJ, Stead D. Thomson CG, et al. Among authors: smith aj. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1388-91. doi: 10.1016/j.bmcl.2005.11.041. Bioorg Med Chem Lett. 2006. PMID: 16321523

8

A morphology- and kinetics-based cascade for human neural cell high content screening.

Richards GR, Smith AJ, Parry F, Platts A, Chan GK, Leveridge M, Kerby JE, Simpson PB. Richards GR, et al. Among authors: smith aj. Assay Drug Dev Technol. 2006 Apr;4(2):143-52. doi: 10.1089/adt.2006.4.143. Assay Drug Dev Technol. 2006. PMID: 16712418

9

Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1.

Blackaby WP, Lewis RT, Thomson JL, Jennings AS, Goodacre SC, Street LJ, MacLeod AM, Pike A, Wood S, Thomas S, Brown TA, Smith A, Pillai G, Almond S, Guscott MR, Burns HD, Eng W, Ryan C, Cook J, Hamill TG. Blackaby WP, et al. ACS Med Chem Lett. 2010 Jun 25;1(7):350-4. doi: 10.1021/ml1001085. eCollection 2010 Oct 14. ACS Med Chem Lett. 2010. PMID: 24900218 Free PMC article.

10

The JAK3 inhibitor WHI-P154 prevents PDGF-evoked process outgrowth in human neural precursor cells.

Richards GR, Smith AJ, Cuddon P, Ma QP, Leveridge M, Kerby J, Roderick HL, Bootman MD, Simpson PB. Richards GR, et al. Among authors: smith aj. J Neurochem. 2006 Apr;97(1):201-10. doi: 10.1111/j.1471-4159.2006.03723.x. Epub 2006 Mar 3. J Neurochem. 2006. PMID: 16515549 Free article.

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