Simpson PB - Search Results

1

Multiple structural features of steroids mediate subtype-selective effects on human alpha4beta3delta GABAA receptors.

Pillai GV, Smith AJ, Hunt PA, Simpson PB. Pillai GV, et al. Among authors: simpson pb. Biochem Pharmacol. 2004 Sep 1;68(5):819-31. doi: 10.1016/j.bcp.2004.05.013. Biochem Pharmacol. 2004. PMID: 15294445

2

Methodological approaches for the study of GABA(A) receptor pharmacology and functional responses.

Smith AJ, Simpson PB. Smith AJ, et al. Among authors: simpson pb. Anal Bioanal Chem. 2003 Nov;377(5):843-51. doi: 10.1007/s00216-003-2172-y. Epub 2003 Aug 23. Anal Bioanal Chem. 2003. PMID: 12937886 Review.

3

Compounds exhibiting selective efficacy for different beta subunits of human recombinant gamma-aminobutyric acid A receptors.

Smith AJ, Oxley B, Malpas S, Pillai GV, Simpson PB. Smith AJ, et al. Among authors: simpson pb. J Pharmacol Exp Ther. 2004 Nov;311(2):601-9. doi: 10.1124/jpet.104.070342. Epub 2004 Jun 21. J Pharmacol Exp Ther. 2004. PMID: 15210837

4

A new pyridazine series of GABAA alpha5 ligands.

van Niel MB, Wilson K, Adkins CH, Atack JR, Castro JL, Clarke DE, Fletcher S, Gerhard U, Mackey MM, Malpas S, Maubach K, Newman R, O'Connor D, Pillai GV, Simpson PB, Thomas SR, MacLeod AM. van Niel MB, et al. Among authors: simpson pb. J Med Chem. 2005 Sep 22;48(19):6004-11. doi: 10.1021/jm050249x. J Med Chem. 2005. PMID: 16162003

5

alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential.

Adkins CE, Pillai GV, Kerby J, Bonnert TP, Haldon C, McKernan RM, Gonzalez JE, Oades K, Whiting PJ, Simpson PB. Adkins CE, et al. Among authors: simpson pb. J Biol Chem. 2001 Oct 19;276(42):38934-9. doi: 10.1074/jbc.M104318200. Epub 2001 Aug 8. J Biol Chem. 2001. PMID: 11495904 Free article.

6

Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors.

Thompson SA, Wheat L, Brown NA, Wingrove PB, Pillai GV, Whiting PJ, Adkins C, Woodward CH, Smith AJ, Simpson PB, Collins I, Wafford KA. Thompson SA, et al. Among authors: simpson pb. Br J Pharmacol. 2004 May;142(1):97-106. doi: 10.1038/sj.bjp.0705689. Epub 2004 Apr 20. Br J Pharmacol. 2004. PMID: 15100159 Free PMC article.

7

Characterisation of a sphingosine 1-phosphate-activated Ca2+ signalling pathway in human neuroblastoma cells.

Villullas IR, Smith AJ, Heavens RP, Simpson PB. Villullas IR, et al. Among authors: simpson pb. J Neurosci Res. 2003 Jul 15;73(2):215-26. doi: 10.1002/jnr.10636. J Neurosci Res. 2003. PMID: 12836164

8

Pharmacology of recombinant human GABA(A) receptor subtypes measured using a novel pH-based high-throughput functional efficacy assay.

Simpson PB, Woollacott AJ, Pillai GV, Maubach KA, Hadingham KL, Martin K, Choudhury HI, Seabrook GR. Simpson PB, et al. J Neurosci Methods. 2000 Jun 30;99(1-2):91-100. doi: 10.1016/s0165-0270(00)00219-3. J Neurosci Methods. 2000. PMID: 10936648

9

A morphology- and kinetics-based cascade for human neural cell high content screening.

Richards GR, Smith AJ, Parry F, Platts A, Chan GK, Leveridge M, Kerby JE, Simpson PB. Richards GR, et al. Among authors: simpson pb. Assay Drug Dev Technol. 2006 Apr;4(2):143-52. doi: 10.1089/adt.2006.4.143. Assay Drug Dev Technol. 2006. PMID: 16712418

10

The JAK3 inhibitor WHI-P154 prevents PDGF-evoked process outgrowth in human neural precursor cells.

Richards GR, Smith AJ, Cuddon P, Ma QP, Leveridge M, Kerby J, Roderick HL, Bootman MD, Simpson PB. Richards GR, et al. Among authors: simpson pb. J Neurochem. 2006 Apr;97(1):201-10. doi: 10.1111/j.1471-4159.2006.03723.x. Epub 2006 Mar 3. J Neurochem. 2006. PMID: 16515549 Free article.

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