The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA.
Daliry A, Pires MQ, Silva CF, Pacheco RS, Munde M, Stephens CE, Kumar A, Ismail MA, Liu Z, Farahat AA, Akay S, Som P, Hu Q, Boykin DW, Wilson WD, De Castro SL, Soeiro MN.
Daliry A, et al. Among authors: hu q.
Antimicrob Agents Chemother. 2011 Oct;55(10):4765-73. doi: 10.1128/AAC.00229-11. Epub 2011 Aug 1.
Antimicrob Agents Chemother. 2011.
PMID: 21807972
Free PMC article.