Alp NJ - Search Results

1

Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo.

Schäfer A, Alp NJ, Cai S, Lygate CA, Neubauer S, Eigenthaler M, Bauersachs J, Channon KM. Schäfer A, et al. Among authors: alp nj. Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1720-6. doi: 10.1161/01.ATV.0000138072.76902.dd. Epub 2004 Jul 8. Arterioscler Thromb Vasc Biol. 2004. PMID: 15242858

2

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.

Alp NJ, Channon KM. Alp NJ, et al. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):413-20. doi: 10.1161/01.ATV.0000110785.96039.f6. Epub 2003 Dec 4. Arterioscler Thromb Vasc Biol. 2004. PMID: 14656731 Review.

3

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.

Alp NJ, McAteer MA, Khoo J, Choudhury RP, Channon KM. Alp NJ, et al. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):445-50. doi: 10.1161/01.ATV.0000115637.48689.77. Epub 2004 Jan 5. Arterioscler Thromb Vasc Biol. 2004. PMID: 14707037

4

Altered plasma versus vascular biopterins in human atherosclerosis reveal relationships between endothelial nitric oxide synthase coupling, endothelial function, and inflammation.

Antoniades C, Shirodaria C, Crabtree M, Rinze R, Alp N, Cunnington C, Diesch J, Tousoulis D, Stefanadis C, Leeson P, Ratnatunga C, Pillai R, Channon KM. Antoniades C, et al. Circulation. 2007 Dec 11;116(24):2851-9. doi: 10.1161/CIRCULATIONAHA.107.704155. Epub 2007 Nov 26. Circulation. 2007. PMID: 18040031

5

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.

Cai S, Khoo J, Mussa S, Alp NJ, Channon KM. Cai S, et al. Among authors: alp nj. Diabetologia. 2005 Sep;48(9):1933-40. doi: 10.1007/s00125-005-1857-5. Epub 2005 Jul 21. Diabetologia. 2005. PMID: 16034613

6

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.

Adlam D, Bendall JK, De Bono JP, Alp NJ, Khoo J, Nicoli T, Yokoyama M, Kawashima S, Channon KM. Adlam D, et al. Among authors: alp nj. Exp Physiol. 2007 Jan;92(1):119-26. doi: 10.1113/expphysiol.2006.035113. Epub 2006 Sep 28. Exp Physiol. 2007. PMID: 17012144 Free article.

7

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.

Cai S, Alp NJ, McDonald D, Smith I, Kay J, Canevari L, Heales S, Channon KM. Cai S, et al. Among authors: alp nj. Cardiovasc Res. 2002 Sep;55(4):838-49. doi: 10.1016/s0008-6363(02)00460-1. Cardiovasc Res. 2002. PMID: 12176133

8

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.

Alp NJ, Mussa S, Khoo J, Cai S, Guzik T, Jefferson A, Goh N, Rockett KA, Channon KM. Alp NJ, et al. J Clin Invest. 2003 Sep;112(5):725-35. doi: 10.1172/JCI17786. J Clin Invest. 2003. PMID: 12952921 Free PMC article.

9

EPR quantification of vascular nitric oxide production in genetically modified mouse models.

Khoo JP, Alp NJ, Bendall JK, Kawashima S, Yokoyama M, Zhang YH, Casadei B, Channon KM. Khoo JP, et al. Among authors: alp nj. Nitric Oxide. 2004 May;10(3):156-61. doi: 10.1016/j.niox.2004.04.003. Nitric Oxide. 2004. PMID: 15158695

10

Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse.

Khoo JP, Nicoli T, Alp NJ, Fullerton J, Flint J, Channon KM. Khoo JP, et al. Among authors: alp nj. Mol Genet Metab. 2004 Jul;82(3):251-4. doi: 10.1016/j.ymgme.2004.04.006. Mol Genet Metab. 2004. PMID: 15234340

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