Artico M - Search Results

1

Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations.

Silvestri R, Artico M, De Martino G, La Regina G, Loddo R, La Colla M, Mura M, La Colla P. Silvestri R, et al. Among authors: artico m. J Med Chem. 2004 Jul 15;47(15):3892-6. doi: 10.1021/jm031147e. J Med Chem. 2004. PMID: 15239667

2

2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones.

Artico M, Silvestri R, Massa S, Loi AG, Corrias S, Piras G, La Colla P. Artico M, et al. J Med Chem. 1996 Jan 19;39(2):522-30. doi: 10.1021/jm950568w. J Med Chem. 1996. PMID: 8558522

3

5H-pyrrolo[1,2-b] [1,2,5]benzothiadiazepines (PBTDs): a novel class of non-nucleoside reverse transcriptase inhibitors.

Artico M, Silvestri R, Pagnozzi E, Stefancich G, Massa S, Loi AG, Putzolu M, Corrias S, Spiga MG, La Colla P. Artico M, et al. Bioorg Med Chem. 1996 Jun;4(6):837-50. doi: 10.1016/0968-0896(96)00075-2. Bioorg Med Chem. 1996. PMID: 8818233

4

Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series.

Mai A, Artico M, Sbardella G, Quartarone S, Massa S, Loi AG, De Montis A, Scintu F, Putzolu M, La Colla P. Mai A, et al. Among authors: artico m. J Med Chem. 1997 May 9;40(10):1447-54. doi: 10.1021/jm960802y. J Med Chem. 1997. PMID: 9154967

5

Synthesis and biological evaluation of 5H-indolo [3,2-b][1,5]benzothiazepine derivatives, designed as conformationally constrained analogues of the human immunodeficiency virus type 1 reverse transcriptase inhibitor L-737,126.

Silvestri R, Artico M, Bruno B, Massa S, Novellino E, Greco G, Marongiu ME, Pani A, De Montis A, La Colla P. Silvestri R, et al. Among authors: artico m. Antivir Chem Chemother. 1998 Mar;9(2):139-48. doi: 10.1177/095632029800900205. Antivir Chem Chemother. 1998. PMID: 9875385

6

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.

Mai A, Artico M, Sbardella G, Massa S, Novellino E, Greco G, Loi AG, Tramontano E, Marongiu ME, La Colla P. Mai A, et al. Among authors: artico m. J Med Chem. 1999 Feb 25;42(4):619-27. doi: 10.1021/jm980260f. J Med Chem. 1999. PMID: 10052969

7

1-[2-(Diphenylmethoxy)ethyl]-2-methyl-5-nitroimidazole: a potent lead for the design of novel NNRTIs.

Silvestri R, Artico M, Massa S, Marceddu T, De Montis F, La Colla P. Silvestri R, et al. Among authors: artico m. Bioorg Med Chem Lett. 2000 Feb 7;10(3):253-6. doi: 10.1016/s0960-894x(99)00664-2. Bioorg Med Chem Lett. 2000. PMID: 10698447

8

Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar concentrations.

Artico M, Silvestri R, Pagnozzi E, Bruno B, Novellino E, Greco G, Massa S, Ettorre A, Loi AG, Scintu F, La Colla P. Artico M, et al. J Med Chem. 2000 May 4;43(9):1886-91. doi: 10.1021/jm9901125. J Med Chem. 2000. PMID: 10794705

Pyrrolyl aryl sulfones (PASs) have been recently reported as a new class of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) inhibitors acting at the non-nucleoside binding site of this enzyme (Artico, M.; et al. J. Med. Chem. 1996, 39, 522-530 …

Pyrrolyl aryl sulfones (PASs) have been recently reported as a new class of human immunodeficiency virus type 1 (HIV-1) reverse transcriptas …

9

Computer-assisted design, synthesis and biological evaluation of novel pyrrolyl heteroaryl sulfones targeted at HIV-1 reverse transcriptase as non-nucleoside inhibitors.

Silvestri R, Artico M, De Martino G, Novellino E, Greco G, Lavecchia A, Massa S, Loi AG, Doratiotto S, La Colla P. Silvestri R, et al. Among authors: artico m. Bioorg Med Chem. 2000 Sep;8(9):2305-9. doi: 10.1016/s0968-0896(00)00144-9. Bioorg Med Chem. 2000. PMID: 11026542

10

Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Mai A, Sbardella G, Artico M, Ragno R, Massa S, Novellino E, Greco G, Lavecchia A, Musiu C, La Colla M, Murgioni C, La Colla P, Loddo R. Mai A, et al. Among authors: artico m. J Med Chem. 2001 Aug 2;44(16):2544-54. doi: 10.1021/jm010853h. J Med Chem. 2001. PMID: 11472208

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