Wheeler MB - Search Results

1

Muscle-specific overexpression of CD36 reverses the insulin resistance and diabetes of MKR mice.

Héron-Milhavet L, Haluzik M, Yakar S, Gavrilova O, Pack S, Jou WC, Ibrahimi A, Kim H, Hunt D, Yau D, Asghar Z, Joseph J, Wheeler MB, Abumrad NA, LeRoith D. Héron-Milhavet L, et al. Among authors: wheeler mb. Endocrinology. 2004 Oct;145(10):4667-76. doi: 10.1210/en.2003-1543. Epub 2004 Jul 1. Endocrinology. 2004. PMID: 15231693

2

Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet.

Joseph JW, Koshkin V, Zhang CY, Wang J, Lowell BB, Chan CB, Wheeler MB. Joseph JW, et al. Among authors: wheeler mb. Diabetes. 2002 Nov;51(11):3211-9. doi: 10.2337/diabetes.51.11.3211. Diabetes. 2002. PMID: 12401712

3

Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis.

Kim H, Haluzik M, Asghar Z, Yau D, Joseph JW, Fernandez AM, Reitman ML, Yakar S, Stannard B, Heron-Milhavet L, Wheeler MB, LeRoith D. Kim H, et al. Among authors: wheeler mb. Diabetes. 2003 Jul;52(7):1770-8. doi: 10.2337/diabetes.52.7.1770. Diabetes. 2003. PMID: 12829645

4

Impaired glucose-stimulated insulin secretion, enhanced intraperitoneal insulin tolerance, and increased beta-cell mass in mice lacking the p110gamma isoform of phosphoinositide 3-kinase.

MacDonald PE, Joseph JW, Yau D, Diao J, Asghar Z, Dai F, Oudit GY, Patel MM, Backx PH, Wheeler MB. MacDonald PE, et al. Among authors: wheeler mb. Endocrinology. 2004 Sep;145(9):4078-83. doi: 10.1210/en.2004-0028. Epub 2004 Jul 1. Endocrinology. 2004. PMID: 15231713

5

Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages.

Seaberg RM, Smukler SR, Kieffer TJ, Enikolopov G, Asghar Z, Wheeler MB, Korbutt G, van der Kooy D. Seaberg RM, et al. Among authors: wheeler mb. Nat Biotechnol. 2004 Sep;22(9):1115-24. doi: 10.1038/nbt1004. Epub 2004 Aug 22. Nat Biotechnol. 2004. PMID: 15322557

6

Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.

Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB. Joseph JW, et al. Among authors: wheeler mb. J Biol Chem. 2004 Dec 3;279(49):51049-56. doi: 10.1074/jbc.M409189200. Epub 2004 Sep 23. J Biol Chem. 2004. PMID: 15448158 Free article.

7

Leptin improves insulin resistance and hyperglycemia in a mouse model of type 2 diabetes.

Toyoshima Y, Gavrilova O, Yakar S, Jou W, Pack S, Asghar Z, Wheeler MB, LeRoith D. Toyoshima Y, et al. Among authors: wheeler mb. Endocrinology. 2005 Sep;146(9):4024-35. doi: 10.1210/en.2005-0087. Epub 2005 Jun 9. Endocrinology. 2005. PMID: 15947005

8

Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells.

Diao J, Asghar Z, Chan CB, Wheeler MB. Diao J, et al. Among authors: wheeler mb. J Biol Chem. 2005 Sep 30;280(39):33487-96. doi: 10.1074/jbc.M506276200. Epub 2005 Jul 14. J Biol Chem. 2005. PMID: 16027126 Free article.

9

Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes.

Asghar Z, Yau D, Chan F, Leroith D, Chan CB, Wheeler MB. Asghar Z, et al. Among authors: wheeler mb. Diabetologia. 2006 Jan;49(1):90-9. doi: 10.1007/s00125-005-0045-y. Epub 2005 Dec 15. Diabetologia. 2006. PMID: 16362284

10

cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling protein-2 overexpressing beta-cells.

McQuaid TS, Saleh MC, Joseph JW, Gyulkhandanyan A, Manning-Fox JE, MacLellan JD, Wheeler MB, Chan CB. McQuaid TS, et al. Among authors: wheeler mb. J Endocrinol. 2006 Sep;190(3):669-80. doi: 10.1677/joe.1.06723. J Endocrinol. 2006. PMID: 17003268

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