O'Brien RM - Search Results

1

The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.

Frigeri C, Martin CC, Svitek CA, Oeser JK, Hutton JC, Gannon M, O'Brien RM. Frigeri C, et al. Diabetes. 2004 Jul;53(7):1754-64. doi: 10.2337/diabetes.53.7.1754. Diabetes. 2004. PMID: 15220199

2

Molecular physiology and genetics of NIDDM. Importance of metabolic staging.

Granner DK, O'Brien RM. Granner DK, et al. Diabetes Care. 1992 Mar;15(3):369-95. doi: 10.2337/diacare.15.3.369. Diabetes Care. 1992. PMID: 1559407 Review.

3

PEPCK gene as model of inhibitory effects of insulin on gene transcription.

O'Brien RM, Granner DK. O'Brien RM, et al. Diabetes Care. 1990 Mar;13(3):327-39. doi: 10.2337/diacare.13.3.327. Diabetes Care. 1990. PMID: 2407480 Review.

4

A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin.

Streeper RS, Svitek CA, Chapman S, Greenbaum LE, Taub R, O'Brien RM. Streeper RS, et al. J Biol Chem. 1997 May 2;272(18):11698-701. doi: 10.1074/jbc.272.18.11698. J Biol Chem. 1997. PMID: 9115220 Free article.

5

Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin.

Dickens M, Svitek CA, Culbert AA, O'Brien RM, Tavaré JM. Dickens M, et al. J Biol Chem. 1998 Aug 7;273(32):20144-9. doi: 10.1074/jbc.273.32.20144. J Biol Chem. 1998. PMID: 9685358 Free article.

6

Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription.

Streeper RS, Eaton EM, Ebert DH, Chapman SC, Svitek CA, O'Brien RM. Streeper RS, et al. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9208-13. doi: 10.1073/pnas.95.16.9208. Proc Natl Acad Sci U S A. 1998. PMID: 9689059 Free PMC article.

7

A phorbol ester-insensitive AP-1 motif mediates the stimulatory effect of insulin on rat malic enzyme gene transcription.

Streeper RS, Chapman SC, Ayala JE, Svitek CA, Goldman JK, Cave A, O'Brien RM. Streeper RS, et al. Mol Endocrinol. 1998 Nov;12(11):1778-91. doi: 10.1210/mend.12.11.0199. Mol Endocrinol. 1998. PMID: 9817602

8

Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein.

Arden SD, Zahn T, Steegers S, Webb S, Bergman B, O'Brien RM, Hutton JC. Arden SD, et al. Diabetes. 1999 Mar;48(3):531-42. doi: 10.2337/diabetes.48.3.531. Diabetes. 1999. PMID: 10078553

9

Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.

Ebert DH, Bischof LJ, Streeper RS, Chapman SC, Svitek CA, Goldman JK, Mathews CE, Leiter EH, Hutton JC, O'Brien RM. Ebert DH, et al. Diabetes. 1999 Mar;48(3):543-51. doi: 10.2337/diabetes.48.3.543. Diabetes. 1999. PMID: 10078554

10

Multiple promoter elements are required for the stimulatory effect of insulin on human collagenase-1 gene transcription. Selective effects on activator protein-1 expression may explain the quantitative difference in insulin and phorbol ester action.

Chapman SC, Ayala JE, Streeper RS, Culbert AA, Eaton EM, Svitek CA, Goldman JK, Tavar JM, O'Brien RM. Chapman SC, et al. J Biol Chem. 1999 Jun 25;274(26):18625-34. doi: 10.1074/jbc.274.26.18625. J Biol Chem. 1999. PMID: 10373474 Free article.

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