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Page 1
Hydrophobic acetal and ketal derivatives of mannopeptimycin-alpha and desmethylhexahydromannopeptimycin-alpha: semisynthetic glycopeptides with potent activity against Gram-positive bacteria.
Dushin RG, Wang TZ, Sum PE, He H, Sutherland AG, Ashcroft JS, Graziani EI, Koehn FE, Bradford PA, Petersen PJ, Wheless KL, How D, Torres N, Lenoy EB, Weiss WJ, Lang SA, Projan SJ, Shlaes DM, Mansour TS. Dushin RG, et al. Among authors: weiss wj. J Med Chem. 2004 Jul 1;47(14):3487-90. doi: 10.1021/jm049765y. J Med Chem. 2004. PMID: 15214775
Novel ether derivatives of mannopeptimycin glycopeptide antibiotic.
Sum PE, How D, Torres N, Petersen PJ, Lenoy EB, Weiss WJ, Mansour TS. Sum PE, et al. Among authors: weiss wj. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1151-5. doi: 10.1016/s0960-894x(03)00045-3. Bioorg Med Chem Lett. 2003. PMID: 12643932
Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.
Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR. Venkatesan AM, et al. Among authors: weiss wj. J Med Chem. 2004 Dec 16;47(26):6556-68. doi: 10.1021/jm049680x. J Med Chem. 2004. PMID: 15588091
Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.
Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Yamamura I, Ado M, Tsuyoshi T, Dos Santos O, Gu Y, Sum FW, Li Z, Francisco G, Lin YI, Petersen PJ, Yang Y, Kumagai T, Weiss WJ, Shlaes DM, Knox JR, Mansour TS. Venkatesan AM, et al. Among authors: weiss wj. J Med Chem. 2006 Jul 27;49(15):4623-37. doi: 10.1021/jm060021p. J Med Chem. 2006. PMID: 16854068
5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of beta-lactamases.
Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Ado M, Tsuyoshi T, Dos Santos O, Li Z, Francisco G, Lin YI, Petersen PJ, Yang Y, Weiss WJ, Shlaes DM, Mansour TS. Venkatesan AM, et al. Among authors: weiss wj. Bioorg Med Chem. 2008 Feb 15;16(4):1890-902. doi: 10.1016/j.bmc.2007.11.006. Epub 2007 Nov 5. Bioorg Med Chem. 2008. PMID: 18061461
In vitro and in vivo activities of tigecycline (GAR-936), daptomycin, and comparative antimicrobial agents against glycopeptide-intermediate Staphylococcus aureus and other resistant gram-positive pathogens.
Petersen PJ, Bradford PA, Weiss WJ, Murphy TM, Sum PE, Projan SJ. Petersen PJ, et al. Among authors: weiss wj. Antimicrob Agents Chemother. 2002 Aug;46(8):2595-601. doi: 10.1128/AAC.46.8.2595-2601.2002. Antimicrob Agents Chemother. 2002. PMID: 12121938 Free PMC article.
In vitro and in vivo activities of novel 6-methylidene penems as beta-lactamase inhibitors.
Weiss WJ, Petersen PJ, Murphy TM, Tardio L, Yang Y, Bradford PA, Venkatesan AM, Abe T, Isoda T, Mihira A, Ushirogochi H, Takasake T, Projan S, O'Connell J, Mansour TS. Weiss WJ, et al. Antimicrob Agents Chemother. 2004 Dec;48(12):4589-96. doi: 10.1128/AAC.48.12.4589-4596.2004. Antimicrob Agents Chemother. 2004. PMID: 15561830 Free PMC article.
113 results