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A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels.
Smit P, van Schaik RH, van der Werf M, van den Beld AW, Koper JW, Lindemans J, Pols HA, Brinkmann AO, de Jong FH, Lamberts SW. Smit P, et al. Among authors: van der werf m, van den beld aw, van schaik rh. J Clin Endocrinol Metab. 2005 Sep;90(9):5313-6. doi: 10.1210/jc.2005-0307. Epub 2005 Jun 28. J Clin Endocrinol Metab. 2005. PMID: 15985487
MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine.
Aarnoudse AL, van Schaik RH, Dieleman J, Molokhia M, van Riemsdijk MM, Ligthelm RJ, Overbosch D, van der Heiden IP, Stricker BH. Aarnoudse AL, et al. Among authors: van schaik rh, van riemsdijk mm, van der heiden ip. Clin Pharmacol Ther. 2006 Oct;80(4):367-74. doi: 10.1016/j.clpt.2006.07.003. Clin Pharmacol Ther. 2006. PMID: 17015054
Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes.
Yazdanpanah M, Aulchenko YS, Hofman A, Janssen JA, Sayed-Tabatabaei FA, van Schaik RH, Klungel OH, Stricker BH, Pols HA, Witteman JC, Lamberts SW, Oostra BA, van Duijn CM. Yazdanpanah M, et al. Among authors: van duijn cm, van schaik rh. Diabetes. 2007 Jul;56(7):1905-12. doi: 10.2337/db06-1127. Epub 2007 Apr 19. Diabetes. 2007. PMID: 17446534
Association of graded allele-specific changes in CYP2D6 function with imipramine dose requirement in a large group of depressed patients.
Schenk PW, van Fessem MA, Verploegh-Van Rij S, Mathot RA, van Gelder T, Vulto AG, van Vliet M, Lindemans J, Bruijn JA, van Schaik RH. Schenk PW, et al. Among authors: van gelder t, van fessem ma, van schaik rh, van vliet m. Mol Psychiatry. 2008 Jun;13(6):597-605. doi: 10.1038/sj.mp.4002057. Epub 2007 Jul 31. Mol Psychiatry. 2008. PMID: 17667959
424 results