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Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.
Morales-Corraliza J, Schmidt SD, Mazzella MJ, Berger JD, Wilson DA, Wesson DW, Jucker M, Levy E, Nixon RA, Mathews PM. Morales-Corraliza J, et al. Among authors: mathews pm. Neurobiol Aging. 2013 Jan;34(1):137-45. doi: 10.1016/j.neurobiolaging.2012.04.007. Epub 2012 May 18. Neurobiol Aging. 2013. PMID: 22608241 Free PMC article.
Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.
Jiang Y, Rigoglioso A, Peterhoff CM, Pawlik M, Sato Y, Bleiwas C, Stavrides P, Smiley JF, Ginsberg SD, Mathews PM, Levy E, Nixon RA. Jiang Y, et al. Among authors: mathews pm. Neurobiol Aging. 2016 Mar;39:90-8. doi: 10.1016/j.neurobiolaging.2015.11.013. Epub 2015 Dec 2. Neurobiol Aging. 2016. PMID: 26923405 Free PMC article.
Cystatin C in aging and in Alzheimer's disease.
Mathews PM, Levy E. Mathews PM, et al. Ageing Res Rev. 2016 Dec;32:38-50. doi: 10.1016/j.arr.2016.06.003. Epub 2016 Jun 19. Ageing Res Rev. 2016. PMID: 27333827 Free PMC article. Review.
Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.
Mathews PM, Guerra CB, Jiang Y, Grbovic OM, Kao BH, Schmidt SD, Dinakar R, Mercken M, Hille-Rehfeld A, Rohrer J, Mehta P, Cataldo AM, Nixon RA. Mathews PM, et al. J Biol Chem. 2002 Feb 15;277(7):5299-307. doi: 10.1074/jbc.M108161200. Epub 2001 Sep 10. J Biol Chem. 2002. PMID: 11551970 Free article.
131 results