Millar RP - Search Results

1

Serine residues 338 and 339 in the carboxyl-terminal tail of the type II gonadotropin-releasing hormone receptor are critical for beta-arrestin-independent internalization.

Ronacher K, Matsiliza N, Nkwanyana N, Pawson AJ, Adam T, Flanagan CA, Millar RP, Katz AA. Ronacher K, et al. Among authors: millar rp. Endocrinology. 2004 Oct;145(10):4480-8. doi: 10.1210/en.2004-0075. Epub 2004 Jun 17. Endocrinology. 2004. PMID: 15205374

2

Loss-of-Function Mutations in the Human Luteinizing Hormone Receptor Predominantly Cause Intracellular Retention.

Newton CL, Anderson RC, Katz AA, Millar RP. Newton CL, et al. Among authors: millar rp. Endocrinology. 2016 Nov;157(11):4364-4377. doi: 10.1210/en.2016-1104. Epub 2016 Aug 17. Endocrinology. 2016. PMID: 27533885

3

Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail Are critical.

Pawson AJ, Maudsley SR, Lopes J, Katz AA, Sun YM, Davidson JS, Millar RP. Pawson AJ, et al. Among authors: millar rp. Endocrinology. 2003 Sep;144(9):3860-71. doi: 10.1210/en.2003-0028. Endocrinology. 2003. PMID: 12933659

4

Pro7.33(303) of the human GnRH receptor regulates selective binding of mammalian GnRH.

Fromme BJ, Katz AA, Millar RP, Flanagan CA. Fromme BJ, et al. Among authors: millar rp. Mol Cell Endocrinol. 2004 Apr 30;219(1-2):47-59. doi: 10.1016/j.mce.2004.01.009. Mol Cell Endocrinol. 2004. PMID: 15149726

5

Outside-in and inside-out signaling: the new concept that selectivity of ligand binding at the gonadotropin-releasing hormone receptor is modulated by the intracellular environment.

Millar RP, Pawson AJ. Millar RP, et al. Endocrinology. 2004 Aug;145(8):3590-3. doi: 10.1210/en.2004-0461. Endocrinology. 2004. PMID: 15265825 No abstract available.

6

Inhibition of human type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment.

Pawson AJ, Maudsley S, Morgan K, Davidson L, Naor Z, Millar RP. Pawson AJ, et al. Among authors: millar rp. Endocrinology. 2005 Jun;146(6):2639-49. doi: 10.1210/en.2005-0133. Epub 2005 Mar 10. Endocrinology. 2005. PMID: 15761034

7

Bovine and ovine gonadotropin-releasing hormone (GnRH)-II ligand precursors and type II GnRH receptor genes are functionally inactivated.

Morgan K, Sellar R, Pawson AJ, Lu ZL, Millar RP. Morgan K, et al. Among authors: millar rp. Endocrinology. 2006 Nov;147(11):5041-51. doi: 10.1210/en.2006-0222. Epub 2006 Aug 17. Endocrinology. 2006. PMID: 16916952

8

Conserved amino acid residues that are important for ligand binding in the type I gonadotropin-releasing hormone (GnRH) receptor are required for high potency of GnRH II at the type II GnRH receptor.

Mamputha S, Lu ZL, Roeske RW, Millar RP, Katz AA, Flanagan CA. Mamputha S, et al. Among authors: millar rp. Mol Endocrinol. 2007 Jan;21(1):281-92. doi: 10.1210/me.2006-0150. Epub 2006 Sep 14. Mol Endocrinol. 2007. PMID: 16973761

9

Mammalian type I gonadotropin-releasing hormone receptors undergo slow, constitutive, agonist-independent internalization.

Pawson AJ, Faccenda E, Maudsley S, Lu ZL, Naor Z, Millar RP. Pawson AJ, et al. Among authors: millar rp. Endocrinology. 2008 Mar;149(3):1415-22. doi: 10.1210/en.2007-1159. Epub 2007 Nov 26. Endocrinology. 2008. PMID: 18039780

10

Changes to gonadotropin-releasing hormone (GnRH) receptor extracellular loops differentially affect GnRH analog binding and activation: evidence for distinct ligand-stabilized receptor conformations.

Pfleger KD, Pawson AJ, Millar RP. Pfleger KD, et al. Among authors: millar rp. Endocrinology. 2008 Jun;149(6):3118-29. doi: 10.1210/en.2008-0002. Epub 2008 Mar 20. Endocrinology. 2008. PMID: 18356273

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