Saarialho-Kere U - Search Results

1

Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.

Elomaa O, Majuri I, Suomela S, Asumalahti K, Jiao H, Mirzaei Z, Rozell B, Dahlman-Wright K, Pispa J, Kere J, Saarialho-Kere U. Elomaa O, et al. Hum Mol Genet. 2004 Aug 1;13(15):1551-61. doi: 10.1093/hmg/ddh178. Epub 2004 Jun 9. Hum Mol Genet. 2004. PMID: 15190014

2

Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.

Asumalahti K, Veal C, Laitinen T, Suomela S, Allen M, Elomaa O, Moser M, de Cid R, Ripatti S, Vorechovsky I, Marcusson JA, Nakagawa H, Lazaro C, Estivill X, Capon F, Novelli G, Saarialho-Kere U, Barker J, Trembath R, Kere J; Psoriasis Consortium. Asumalahti K, et al. Hum Mol Genet. 2002 Mar 1;11(5):589-97. doi: 10.1093/hmg/11.5.589. Hum Mol Genet. 2002. PMID: 11875053

3

Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.

Asumalahti K, Ameen M, Suomela S, Hagforsen E, Michaëlsson G, Evans J, Munro M, Veal C, Allen M, Leman J, David Burden A, Kirby B, Connolly M, Griffiths CE, Trembath RC, Kere J, Saarialho-Kere U, Barker JN. Asumalahti K, et al. J Invest Dermatol. 2003 Apr;120(4):627-32. doi: 10.1046/j.1523-1747.2003.12094.x. J Invest Dermatol. 2003. PMID: 12648227 Free article.

4

Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1.

Asumalahti K, Laitinen T, Lahermo P, Suomela S, Itkonen-Vatjus R, Jansen C, Karvonen J, Karvonen SL, Reunala T, Snellman E, Uurasmaa T, Saarialho-Kere U, Kere J. Asumalahti K, et al. J Invest Dermatol. 2003 Oct;121(4):735-40. doi: 10.1046/j.1523-1747.2003.12483.x. J Invest Dermatol. 2003. PMID: 14632189 Free article.

5

HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes.

Suomela S, Elomaa O, Asumalahti K, Kariniemi AL, Karvonen SL, Peltonen J, Kere J, Saarialho-Kere U. Suomela S, et al. J Invest Dermatol. 2003 Dec;121(6):1360-4. doi: 10.1046/j.1523-1747.2003.12642.x. J Invest Dermatol. 2003. PMID: 14675183 Free article.

6

The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.

Tiala I, Suomela S, Huuhtanen J, Wakkinen J, Hölttä-Vuori M, Kainu K, Ranta S, Turpeinen U, Hämäläinen E, Jiao H, Karvonen SL, Ikonen E, Kere J, Saarialho-Kere U, Elomaa O. Tiala I, et al. J Mol Med (Berl). 2007 Jun;85(6):589-601. doi: 10.1007/s00109-006-0155-0. Epub 2007 Jan 13. J Mol Med (Berl). 2007. PMID: 17221218

7

The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice.

Tiala I, Wakkinen J, Suomela S, Puolakkainen P, Tammi R, Forsberg S, Rollman O, Kainu K, Rozell B, Kere J, Saarialho-Kere U, Elomaa O. Tiala I, et al. Hum Mol Genet. 2008 Apr 1;17(7):1043-51. doi: 10.1093/hmg/ddm377. Epub 2008 Jan 3. Hum Mol Genet. 2008. PMID: 18174193

8

A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele.

Asumalahti K, Laitinen T, Itkonen-Vatjus R, Lokki ML, Suomela S, Snellman E, Saarialho-Kere U, Kere J. Asumalahti K, et al. Hum Mol Genet. 2000 Jun 12;9(10):1533-42. doi: 10.1093/hmg/9.10.1533. Hum Mol Genet. 2000. PMID: 10888604

9

Interferon alpha-inducible protein 27 (IFI27) is upregulated in psoriatic skin and certain epithelial cancers.

Suomela S, Cao L, Bowcock A, Saarialho-Kere U. Suomela S, et al. J Invest Dermatol. 2004 Mar;122(3):717-21. doi: 10.1111/j.0022-202X.2004.22322.x. J Invest Dermatol. 2004. PMID: 15086558 Free article.

10

Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis.

Suomela S, Kainu K, Onkamo P, Tiala I, Himberg J, Koskinen L, Snellman E, Karvonen SL, Karvonen J, Uurasmaa T, Reunala T, Kivikäs K, Jansén CT, Holopainen P, Elomaa O, Kere J, Saarialho-Kere U. Suomela S, et al. Acta Derm Venereol. 2007;87(2):127-34. doi: 10.2340/00015555-0184. Acta Derm Venereol. 2007. PMID: 17340018 Free article.

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