Down-regulation of SKP2 induces apoptosis in lung-cancer cells.
Yokoi S, Yasui K, Iizasa T, Takahashi T, Fujisawa T, Inazawa J.
Yokoi S, et al.
Cancer Sci. 2003 Apr;94(4):344-9. doi: 10.1111/j.1349-7006.2003.tb01444.x.
Cancer Sci. 2003.
PMID: 12824902
Free PMC article.
S-Phase kinase associated protein 2 (SKP2), an F-box protein constituting the substrate-recognition subunit of the SCF(SKP2) ubiquitin ligase complex, targets cell-cycle regulators, such as the cyclin-dependent kinase inhibitor p27(KIP1), for ubiquitin-mediated degradation …
S-Phase kinase associated protein 2 (SKP2), an F-box protein constituting the substrate-recognition subunit of the SCF(SKP2) ubiquiti …