Ruthardt M - Search Results

1

In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors.

Brieger A, Boehrer S, Schaaf S, Nowak D, Ruthardt M, Kim SZ, Atadja P, Hoelzer D, Mitrou PS, Weidmann E, Chow KU. Brieger A, et al. Among authors: ruthardt m. Biochem Pharmacol. 2004 Jul 1;68(1):85-93. doi: 10.1016/j.bcp.2004.02.028. Biochem Pharmacol. 2004. PMID: 15183120

2

PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.

Sternsdorf T, Puccetti E, Jensen K, Hoelzer D, Will H, Ottmann OG, Ruthardt M. Sternsdorf T, et al. Among authors: ruthardt m. Mol Cell Biol. 1999 Jul;19(7):5170-8. doi: 10.1128/MCB.19.7.5170. Mol Cell Biol. 1999. PMID: 10373566 Free PMC article.

3

BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity.

Puccetti E, Güller S, Orleth A, Brüggenolte N, Hoelzer D, Ottmann OG, Ruthardt M. Puccetti E, et al. Among authors: ruthardt m. Cancer Res. 2000 Jul 1;60(13):3409-13. Cancer Res. 2000. PMID: 10910048

4

Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia.

Boehrer S, Chow KU, Puccetti E, Ruthardt M, Godzisard S, Krapohl A, Schneider B, Hoelzer D, Mitrou PS, Rangnekar VM, Weidmann E. Boehrer S, et al. Among authors: ruthardt m. Hematol J. 2001;2(2):103-7. doi: 10.1038/sj/thj/6200089. Hematol J. 2001. PMID: 11424002

5

In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation.

Boehrer S, Chow KU, Beske F, Kukoc-Zivojnov N, Puccetti E, Ruthardt M, Baum C, Rangnekar VM, Hoelzer D, Mitrou PS, Weidmann E. Boehrer S, et al. Among authors: ruthardt m. Cancer Res. 2002 Mar 15;62(6):1768-75. Cancer Res. 2002. PMID: 11912153

6

Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.

Puccetti E, Sennewald B, Fosca-Ferrara F, Boehrer S, Bianchini A, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: ruthardt m. Hematol J. 2001;2(6):385-92. doi: 10.1038/sj.thj.6200138. Hematol J. 2001. PMID: 11920278

7

Folinic acid antagonizes methotrexate-induced differentiation of monocyte progenitors.

Möller B, Kukoc-Zivojnov N, Okamgba S, Kessler U, Puccetti E, Ottmann OG, Kaltwasser JP, Hoelzer D, Ruthardt M. Möller B, et al. Among authors: ruthardt m. Rheumatol Int. 2002 Jun;22(2):60-7. doi: 10.1007/s00296-002-0188-9. Epub 2002 Apr 20. Rheumatol Int. 2002. PMID: 12070677

8

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

Puccetti E, Obradovic D, Beissert T, Bianchini A, Washburn B, Chiaradonna F, Boehrer S, Hoelzer D, Ottmann OG, Pelicci PG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: ruthardt m. Cancer Res. 2002 Dec 1;62(23):7050-8. Cancer Res. 2002. PMID: 12460926

9

Expression and function of prostate-apoptosis-response-gene-4 in lymphatic cells.

Boehrer S, Chow KU, Ruthardt M, Hoelzer D, Mitrou PS, Weidmann E. Boehrer S, et al. Among authors: ruthardt m. Leuk Lymphoma. 2002 Sep;43(9):1737-41. doi: 10.1080/1042819021000006510. Leuk Lymphoma. 2002. PMID: 12685825

10

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

Beissert T, Puccetti E, Bianchini A, Güller S, Boehrer S, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Beissert T, et al. Among authors: ruthardt m. Blood. 2003 Oct 15;102(8):2985-93. doi: 10.1182/blood-2003-03-0811. Epub 2003 Jun 26. Blood. 2003. PMID: 12829585 Free article.

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