Sutherland M - Search Results

1

Lead identification of a potent benzopyranone selective estrogen receptor modulator.

McKie JA, Bhagwat SS, Brady H, Doubleday M, Gayo L, Hickman M, Jalluri RK, Khammungkhune S, Kois A, Mortensen D, Richard N, Sapienza J, Shevlin G, Stein B, Sutherland M. McKie JA, et al. Among authors: sutherland m. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3407-10. doi: 10.1016/j.bmcl.2004.04.081. Bioorg Med Chem Lett. 2004. PMID: 15177442

2

Effects of SP500263, a novel selective estrogen receptor modulator, on bone, uterus, and serum cholesterol in the ovariectomized rat.

Sutherland MK, Brady H, Gayo-Fung LM, Leisten J, Lipps SG, McKie JA, O'Leary E, Patnaik N, Anderson DW, Bhagwat SS, Stein B. Sutherland MK, et al. Calcif Tissue Int. 2003 Jun;72(6):710-6. doi: 10.1007/s00223-002-1029-2. Calcif Tissue Int. 2003. PMID: 14563000

3

Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator.

Brady H, Doubleday M, Gayo-Fung LM, Hickman M, Khammungkhune S, Kois A, Lipps S, Pierce S, Richard N, Shevlin G, Sutherland MK, Anderson DW, Bhagwat SS, Stein B. Brady H, et al. Among authors: sutherland mk. Mol Pharmacol. 2002 Mar;61(3):562-8. doi: 10.1124/mol.61.3.562. Mol Pharmacol. 2002. PMID: 11854436

4

Effects of SP500263, a novel, potent antiestrogen, on breast cancer cells and in xenograft models.

Brady H, Desai S, Gayo-Fung LM, Khammungkhune S, McKie JA, O'Leary E, Pascasio L, Sutherland MK, Anderson DW, Bhagwat SS, Stein B. Brady H, et al. Among authors: sutherland mk. Cancer Res. 2002 Mar 1;62(5):1439-42. Cancer Res. 2002. PMID: 11888917

5

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers.

Smith LM, Nesterova A, Ryan MC, Duniho S, Jonas M, Anderson M, Zabinski RF, Sutherland MK, Gerber HP, Van Orden KL, Moore PA, Ruben SM, Carter PJ. Smith LM, et al. Among authors: sutherland mk. Br J Cancer. 2008 Jul 8;99(1):100-9. doi: 10.1038/sj.bjc.6604437. Epub 2008 Jun 10. Br J Cancer. 2008. PMID: 18542072 Free PMC article.

6

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody-drug conjugate SGN-75.

Ryan MC, Kostner H, Gordon KA, Duniho S, Sutherland MK, Yu C, Kim KM, Nesterova A, Anderson M, McEarchern JA, Law CL, Smith LM. Ryan MC, et al. Among authors: sutherland mk. Br J Cancer. 2010 Aug 24;103(5):676-84. doi: 10.1038/sj.bjc.6605816. Epub 2010 Jul 27. Br J Cancer. 2010. PMID: 20664585 Free PMC article.

7

Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.

Sutherland MK, Yu C, Lewis TS, Miyamoto JB, Morris-Tilden CA, Jonas M, Sutherland J, Nesterova A, Gerber HP, Sievers EL, Grewal IS, Law CL. Sutherland MK, et al. Among authors: sutherland j. MAbs. 2009 Sep-Oct;1(5):481-90. doi: 10.4161/mabs.1.5.9288. Epub 2009 Sep 15. MAbs. 2009. PMID: 20065652 Free PMC article.

8

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia.

Li F, Sutherland MK, Yu C, Walter RB, Westendorf L, Valliere-Douglass J, Pan L, Cronkite A, Sussman D, Klussman K, Ulrich M, Anderson ME, Stone IJ, Zeng W, Jonas M, Lewis TS, Goswami M, Wang SA, Senter PD, Law CL, Feldman EJ, Benjamin DR. Li F, et al. Among authors: sutherland mk. Mol Cancer Ther. 2018 Feb;17(2):554-564. doi: 10.1158/1535-7163.MCT-17-0742. Epub 2017 Nov 15. Mol Cancer Ther. 2018. PMID: 29142066

9

5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.

Sutherland MK, Yu C, Anderson M, Zeng W, van Rooijen N, Sievers EL, Grewal IS, Law CL. Sutherland MK, et al. MAbs. 2010 Jul-Aug;2(4):440-8. doi: 10.4161/mabs.12203. Epub 2010 Jul 1. MAbs. 2010. PMID: 20495353 Free PMC article.

10

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist.

Winkler DG, Sutherland MK, Geoghegan JC, Yu C, Hayes T, Skonier JE, Shpektor D, Jonas M, Kovacevich BR, Staehling-Hampton K, Appleby M, Brunkow ME, Latham JA. Winkler DG, et al. Among authors: sutherland mk. EMBO J. 2003 Dec 1;22(23):6267-76. doi: 10.1093/emboj/cdg599. EMBO J. 2003. PMID: 14633986 Free PMC article.

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