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Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.
Liu Y, Kha H, Ungrin M, Robinson MO, Harrington L. Liu Y, et al. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3597-602. doi: 10.1073/pnas.062549199. Proc Natl Acad Sci U S A. 2002. PMID: 11904422 Free PMC article.
Furthermore, loss of only one copy of mTert also results in telomere shortening intermediate between wild-type (wt) and mTert-null ES cells [Liu, Y., Snow, B. E., Hande, M. P., Yeung, D., Erdmann, N. J., Wakeham, A., Itie, A., Siderovski, D. ...
Furthermore, loss of only one copy of mTert also results in telomere shortening intermediate between wild-type (wt) and mTert-null ES cells …
Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypes.
Stock AJ, McDevitt RA, Puligilla C, Wang Y, Zhang Y, Wang K, Sun C, Becker KG, Lehrmann E, Wood WH 3rd, Gong Y, Aqdas M, Sung MH, Hoffmann V, Liu C, Gorospe M, Harrington L, Ferrucci L, Liu Y. Stock AJ, et al. Among authors: liu y, liu c. PLoS Genet. 2022 Nov 28;18(11):e1010506. doi: 10.1371/journal.pgen.1010506. eCollection 2022 Nov. PLoS Genet. 2022. PMID: 36441670 Free PMC article.
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