Holst LS - Search Results

1

Enhanced cAMP protein kinase A signaling determines improved insulin secretion in a clonal insulin-producing beta-cell line (INS-1 832/13).

Yang S, Fransson U, Fagerhus L, Holst LS, Hohmeier HE, Renström E, Mulder H. Yang S, et al. Among authors: holst ls. Mol Endocrinol. 2004 Sep;18(9):2312-20. doi: 10.1210/me.2004-0148. Epub 2004 May 27. Mol Endocrinol. 2004. PMID: 15166255

2

Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulin.

Härndahl L, Jing XJ, Ivarsson R, Degerman E, Ahrén B, Manganiello VC, Renström E, Holst LS. Härndahl L, et al. Among authors: holst ls. J Biol Chem. 2002 Oct 4;277(40):37446-55. doi: 10.1074/jbc.M205401200. Epub 2002 Aug 6. J Biol Chem. 2002. PMID: 12169692 Free article.

3

Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology.

Härndahl L, Wierup N, Enerbäck S, Mulder H, Manganiello VC, Sundler F, Degerman E, Ahrén B, Holst LS. Härndahl L, et al. Among authors: holst ls. J Biol Chem. 2004 Apr 9;279(15):15214-22. doi: 10.1074/jbc.M308952200. Epub 2004 Jan 20. J Biol Chem. 2004. PMID: 14736883 Free article.

4

Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I.

Holst LS, Mulder H, Manganiello V, Sundler F, Ahrén B, Holm C, Degerman E. Holst LS, et al. Biochem Biophys Res Commun. 1998 Sep 8;250(1):181-6. doi: 10.1006/bbrc.1998.9166. Biochem Biophys Res Commun. 1998. PMID: 9735353

5

Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells.

Mulder H, Holst LS, Svensson H, Degerman E, Sundler F, Ahrén B, Rorsman P, Holm C. Mulder H, et al. Among authors: holst ls. Diabetes. 1999 Jan;48(1):228-32. doi: 10.2337/diabetes.48.1.228. Diabetes. 1999. PMID: 9892250

6

Dual effects of pituitary adenylate cyclase-activating polypeptide and isoproterenol on lipid metabolism and signaling in primary rat adipocytes.

Akesson L, Ahrén B, Manganiello VC, Holst LS, Edgren G, Degerman E. Akesson L, et al. Among authors: holst ls. Endocrinology. 2003 Dec;144(12):5293-9. doi: 10.1210/en.2003-0364. Epub 2003 Aug 28. Endocrinology. 2003. PMID: 12960103

7

Localization of hormone-sensitive lipase to rat Sertoli cells and its expression in developing and degenerating testes.

Holst LS, Hoffmann AM, Mulder H, Sundler F, Holm C, Bergh A, Fredrikson G. Holst LS, et al. FEBS Lett. 1994 Nov 28;355(2):125-30. doi: 10.1016/0014-5793(94)01185-0. FEBS Lett. 1994. PMID: 7982484 Free article.

8

Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase.

Holst LS, Langin D, Mulder H, Laurell H, Grober J, Bergh A, Mohrenweiser HW, Edgren G, Holm C. Holst LS, et al. Genomics. 1996 Aug 1;35(3):441-7. doi: 10.1006/geno.1996.0383. Genomics. 1996. PMID: 8812477

9

Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.

Walz HA, Härndahl L, Wierup N, Zmuda-Trzebiatowska E, Svennelid F, Manganiello VC, Ploug T, Sundler F, Degerman E, Ahrén B, Holst LS. Walz HA, et al. Among authors: holst ls. J Endocrinol. 2006 Jun;189(3):629-41. doi: 10.1677/joe.1.06522. J Endocrinol. 2006. PMID: 16731793

10

Beta-cell PDE3B regulates Ca2+-stimulated exocytosis of insulin.

Walz HA, Wierup N, Vikman J, Manganiello VC, Degerman E, Eliasson L, Holst LS. Walz HA, et al. Among authors: holst ls. Cell Signal. 2007 Jul;19(7):1505-13. doi: 10.1016/j.cellsig.2007.01.030. Epub 2007 Feb 12. Cell Signal. 2007. PMID: 17368848

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