Hegedus T - Search Results

1

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.

Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: hegedus t. Mol Pharmacol. 2004 Jun;65(6):1485-95. doi: 10.1124/mol.65.6.1485. Mol Pharmacol. 2004. PMID: 15155841

2

Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells.

Holló Z, Homolya L, Hegedüs T, Sarkadi B. Holló Z, et al. Among authors: hegedus t. FEBS Lett. 1996 Mar 25;383(1-2):99-104. doi: 10.1016/0014-5793(96)00237-2. FEBS Lett. 1996. PMID: 8612802 Free article.

3

Membrane topology and glycosylation of the human multidrug resistance-associated protein.

Bakos E, Hegedüs T, Holló Z, Welker E, Tusnády GE, Zaman GJ, Flens MJ, Váradi A, Sarkadi B. Bakos E, et al. Among authors: hegedus t. J Biol Chem. 1996 May 24;271(21):12322-6. doi: 10.1074/jbc.271.21.12322. J Biol Chem. 1996. PMID: 8647833 Free article.

4

Parallel functional and immunological detection of human multidrug resistance proteins, P-glycoprotein and MRP1.

Holló Z, Homolya L, Hegedûs T, Müller M, Szakács G, Jakab K, Antal F, Sarkadi B. Holló Z, et al. Among authors: hegedus t. Anticancer Res. 1998 Jul-Aug;18(4C):2981-7. Anticancer Res. 1998. PMID: 9713496

5

Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.

Hegedus T, Orfi L, Seprodi A, Váradi A, Sarkadi B, Kéri G. Hegedus T, et al. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):318-25. doi: 10.1016/s0925-4439(02)00095-9. Biochim Biophys Acta. 2002. PMID: 12084474 Free article. Review.

6

C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins.

Hegedüs T, Sessler T, Scott R, Thelin W, Bakos E, Váradi A, Szabó K, Homolya L, Milgram SL, Sarkadi B. Hegedüs T, et al. Biochem Biophys Res Commun. 2003 Mar 14;302(3):454-61. doi: 10.1016/s0006-291x(03)00196-7. Biochem Biophys Res Commun. 2003. PMID: 12615054

7

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.

Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: hegedus t, hegedus c. J Biol Chem. 2008 Sep 19;283(38):26059-70. doi: 10.1074/jbc.M803230200. Epub 2008 Jul 21. J Biol Chem. 2008. PMID: 18644784 Free PMC article.

8

Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?

Brózik A, Hegedüs C, Erdei Z, Hegedus T, Özvegy-Laczka C, Szakács G, Sarkadi B. Brózik A, et al. Among authors: hegedus t, hegedus c. Expert Opin Drug Metab Toxicol. 2011 May;7(5):623-42. doi: 10.1517/17425255.2011.562892. Epub 2011 Mar 17. Expert Opin Drug Metab Toxicol. 2011. PMID: 21410427 Review.

9

ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions.

Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedus T. Gyimesi G, et al. Among authors: hegedus t. Biochim Biophys Acta. 2011 Dec;1808(12):2954-64. doi: 10.1016/j.bbamem.2011.07.038. Epub 2011 Aug 3. Biochim Biophys Acta. 2011. PMID: 21840296 Free article.

10

ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application.

Gyimesi G, Borsodi D, Sarankó H, Tordai H, Sarkadi B, Hegedűs T. Gyimesi G, et al. Among authors: hegedus t. Hum Mutat. 2012 Nov;33(11):1547-56. doi: 10.1002/humu.22138. Epub 2012 Jul 11. Hum Mutat. 2012. PMID: 22693078

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