Mizui Y - Search Results

1

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities.

Mizui Y, Sakai T, Iwata M, Uenaka T, Okamoto K, Shimizu H, Yamori T, Yoshimatsu K, Asada M. Mizui Y, et al. J Antibiot (Tokyo). 2004 Mar;57(3):188-96. doi: 10.7164/antibiotics.57.188. J Antibiot (Tokyo). 2004. PMID: 15152804 Free article.

2

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening.

Sakai T, Sameshima T, Matsufuji M, Kawamura N, Dobashi K, Mizui Y. Sakai T, et al. Among authors: mizui y. J Antibiot (Tokyo). 2004 Mar;57(3):173-9. doi: 10.7164/antibiotics.57.173. J Antibiot (Tokyo). 2004. PMID: 15152802 Free article.

3

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. II. Physico-chemical properties and structure elucidation.

Sakai T, Asai N, Okuda A, Kawamura N, Mizui Y. Sakai T, et al. Among authors: mizui y. J Antibiot (Tokyo). 2004 Mar;57(3):180-7. doi: 10.7164/antibiotics.57.180. J Antibiot (Tokyo). 2004. PMID: 15152803 Free article.

4

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

Kotake Y, Sagane K, Owa T, Mimori-Kiyosue Y, Shimizu H, Uesugi M, Ishihama Y, Iwata M, Mizui Y. Kotake Y, et al. Among authors: mizui y. Nat Chem Biol. 2007 Sep;3(9):570-5. doi: 10.1038/nchembio.2007.16. Epub 2007 Jul 22. Nat Chem Biol. 2007. PMID: 17643112

5

Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor.

Okamoto K, Ito D, Miyazaki K, Watanabe S, Tohyama O, Yokoi A, Ozawa Y, Asano M, Kawamura T, Yamane Y, Nagao S, Funasaka S, Kamata J, Kotake Y, Aoki M, Tsukahara N, Mizui Y, Tanaka I, Sawada K. Okamoto K, et al. Among authors: mizui y. Int J Mol Med. 2012 Apr;29(4):541-9. doi: 10.3892/ijmm.2011.875. Epub 2011 Dec 29. Int J Mol Med. 2012. PMID: 22211243 Free PMC article.

6

Biological validation that SF3b is a target of the antitumor macrolide pladienolide.

Yokoi A, Kotake Y, Takahashi K, Kadowaki T, Matsumoto Y, Minoshima Y, Sugi NH, Sagane K, Hamaguchi M, Iwata M, Mizui Y. Yokoi A, et al. Among authors: mizui y. FEBS J. 2011 Dec;278(24):4870-80. doi: 10.1111/j.1742-4658.2011.08387.x. Epub 2011 Oct 31. FEBS J. 2011. PMID: 21981285 Free article.

7

Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.

Nagao S, Yamane Y, Funasaka S, Tanaka K, Miyazaki K, Kotake Y, Kamata J, Watanabe-Miyano S, Toyama O, Ozawa Y, Mizui Y, Okamoto K, Ito D. Nagao S, et al. Among authors: mizui y. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29. doi: 10.1016/j.bmc.2014.07.020. Epub 2014 Jul 30. Bioorg Med Chem. 2014. PMID: 25139751

8

Total synthesis of the potent antitumor macrolides pladienolide B and D.

Kanada RM, Itoh D, Nagai M, Niijima J, Asai N, Mizui Y, Abe S, Kotake Y. Kanada RM, et al. Among authors: mizui y. Angew Chem Int Ed Engl. 2007;46(23):4350-5. doi: 10.1002/anie.200604997. Angew Chem Int Ed Engl. 2007. PMID: 17437311 No abstract available.

9

E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-1 and MEK kinase-1: in vitro characterization of its anti-inflammatory and antihyperproliferative activities.

Goto M, Chow J, Muramoto K, Chiba K, Yamamoto S, Fujita M, Obaishi H, Tai K, Mizui Y, Tanaka I, Young D, Yang H, Wang YJ, Shirota H, Gusovsky F. Goto M, et al. Among authors: mizui y. J Pharmacol Exp Ther. 2009 Nov;331(2):485-95. doi: 10.1124/jpet.109.156554. Epub 2009 Aug 14. J Pharmacol Exp Ther. 2009. PMID: 19684251

10

cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter.

Mizui Y, Yamazaki K, Sagane K, Tanaka I. Mizui Y, et al. Gene. 1999 Jun 11;233(1-2):67-74. doi: 10.1016/s0378-1119(99)00155-9. Gene. 1999. PMID: 10375622

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