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Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A.
Honda T, Liby KT, Su X, Sundararajan C, Honda Y, Suh N, Risingsong R, Williams CR, Royce DB, Sporn MB, Gribble GW. Honda T, et al. Among authors: royce db. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6306-9. doi: 10.1016/j.bmcl.2006.09.012. Epub 2006 Sep 25. Bioorg Med Chem Lett. 2006. PMID: 16996735 Free PMC article.
The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer.
Liby K, Rendi M, Suh N, Royce DB, Risingsong R, Williams CR, Lamph W, Labrie F, Krajewski S, Xu X, Kim H, Brown P, Sporn MB. Liby K, et al. Among authors: royce db. Clin Cancer Res. 2006 Oct 1;12(19):5902-9. doi: 10.1158/1078-0432.CCR-06-1119. Clin Cancer Res. 2006. PMID: 17020999
Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Liby K, Risingsong R, Royce DB, Williams CR, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB. Liby K, et al. Among authors: royce db. Clin Cancer Res. 2008 Jul 15;14(14):4556-63. doi: 10.1158/1078-0432.CCR-08-0040. Clin Cancer Res. 2008. PMID: 18628471 Free PMC article.
35 results