Sambamurti K - Search Results

1

Differential expression of cholesterol hydroxylases in Alzheimer's disease.

Brown J 3rd, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Brown J 3rd, et al. Among authors: sambamurti k. J Biol Chem. 2004 Aug 13;279(33):34674-81. doi: 10.1074/jbc.M402324200. Epub 2004 May 17. J Biol Chem. 2004. PMID: 15148325 Free article.

2

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme.

Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB. Eckman EA, et al. Among authors: sambamurti k. J Biol Chem. 2003 Jan 24;278(4):2081-4. doi: 10.1074/jbc.C200642200. Epub 2002 Dec 2. J Biol Chem. 2003. PMID: 12464614 Free article.

3

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein.

Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG. Sambamurti K, et al. J Biol Chem. 1999 Sep 17;274(38):26810-4. doi: 10.1074/jbc.274.38.26810. J Biol Chem. 1999. PMID: 10480887 Free article.

4

Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells.

Refolo LM, Eckman C, Prada CM, Yager D, Sambamurti K, Mehta N, Hardy J, Younkin SG. Refolo LM, et al. Among authors: sambamurti k. J Neurochem. 1999 Dec;73(6):2383-8. doi: 10.1046/j.1471-4159.1999.0732383.x. J Neurochem. 1999. PMID: 10582597 Free article.

5

Characterization of recombinant, soluble beta-secretase from an insect cell expression system.

Mallender WD, Yager D, Onstead L, Nichols MR, Eckman C, Sambamurti K, Kopcho LM, Marcinkeviciene J, Copeland RA, Rosenberry TL. Mallender WD, et al. Among authors: sambamurti k. Mol Pharmacol. 2001 Mar;59(3):619-26. doi: 10.1124/mol.59.3.619. Mol Pharmacol. 2001. PMID: 11179458

6

A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor.

Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K. Pinnix I, et al. Among authors: sambamurti k. J Biol Chem. 2001 Jan 5;276(1):481-7. doi: 10.1074/jbc.M005968200. J Biol Chem. 2001. PMID: 11035007 Free article.

7

Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.

Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: sambamurti k. FASEB J. 2001 Jan;15(1):16-18. doi: 10.1096/fj.00-0528fje. Epub 2000 Nov 9. FASEB J. 2001. PMID: 11099491

8

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo.

Miller BC, Eckman EA, Sambamurti K, Dobbs N, Chow KM, Eckman CB, Hersh LB, Thiele DL. Miller BC, et al. Among authors: sambamurti k. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6221-6. doi: 10.1073/pnas.1031520100. Epub 2003 May 5. Proc Natl Acad Sci U S A. 2003. PMID: 12732730 Free PMC article.

9

Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.

Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambamurti K. Barnwell E, et al. Among authors: sambamurti k. PLoS One. 2014 Mar 21;9(3):e91531. doi: 10.1371/journal.pone.0091531. eCollection 2014. PLoS One. 2014. PMID: 24658363 Free PMC article.

10

Pigment epithelium-derived factor maintains retinal pigment epithelium function by inhibiting vascular endothelial growth factor-R2 signaling through gamma-secretase.

Ablonczy Z, Prakasam A, Fant J, Fauq A, Crosson C, Sambamurti K. Ablonczy Z, et al. Among authors: sambamurti k. J Biol Chem. 2009 Oct 30;284(44):30177-86. doi: 10.1074/jbc.M109.032391. Epub 2009 Sep 1. J Biol Chem. 2009. PMID: 19723623 Free PMC article.

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