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Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.
Kawasumi M, Chiba T, Yamada M, Miyamae-Kaneko M, Matsuoka M, Nakahara J, Tomita T, Iwatsubo T, Kato S, Aiso S, Nishimoto I, Kouyama K. Kawasumi M, et al. Among authors: chiba t. Eur J Neurosci. 2004 May;19(10):2826-38. doi: 10.1111/j.0953-816X.2004.03397.x. Eur J Neurosci. 2004. PMID: 15147316
Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo.
Chiba T, Yamada M, Hashimoto Y, Sato M, Sasabe J, Kita Y, Terashita K, Aiso S, Nishimoto I, Matsuoka M. Chiba T, et al. J Neurosci. 2005 Nov 2;25(44):10252-61. doi: 10.1523/JNEUROSCI.3348-05.2005. J Neurosci. 2005. PMID: 16267233 Free PMC article.
Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization.
Terashita K, Hashimoto Y, Niikura T, Tajima H, Yamagishi Y, Ishizaka M, Kawasumi M, Chiba T, Kanekura K, Yamada M, Nawa M, Kita Y, Aiso S, Nishimoto I. Terashita K, et al. Among authors: chiba t. J Neurochem. 2003 Jun;85(6):1521-38. doi: 10.1046/j.1471-4159.2003.01797.x. J Neurochem. 2003. PMID: 12787071 Free article.
2,670 results