Galm U - Search Results

1

In vitro and in vivo production of new aminocoumarins by a combined biochemical, genetic, and synthetic approach.

Galm U, Dessoy MA, Schmidt J, Wessjohann LA, Heide L. Galm U, et al. Chem Biol. 2004 Feb;11(2):173-83. doi: 10.1016/j.chembiol.2004.01.012. Chem Biol. 2004. PMID: 15123279

2

Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040.

Galm U, Schimana J, Fiedler HP, Schmidt J, Li SM, Heide L. Galm U, et al. Arch Microbiol. 2002 Aug;178(2):102-14. doi: 10.1007/s00203-002-0429-z. Epub 2002 May 14. Arch Microbiol. 2002. PMID: 12115055

3

New aminocoumarin antibiotics from a cloQ-defective mutant of the clorobiocin producer Streptomyces roseochromogenes DS12.976.

Freitag A, Galm U, Li SM, Heide L. Freitag A, et al. Among authors: galm u. J Antibiot (Tokyo). 2004 Mar;57(3):205-9. doi: 10.7164/antibiotics.57.205. J Antibiot (Tokyo). 2004. PMID: 15152806 Free article.

4

Antimicrobial and DNA gyrase-inhibitory activities of novel clorobiocin derivatives produced by mutasynthesis.

Galm U, Heller S, Shapiro S, Page M, Li SM, Heide L. Galm U, et al. Antimicrob Agents Chemother. 2004 Apr;48(4):1307-12. doi: 10.1128/AAC.48.4.1307-1312.2004. Antimicrob Agents Chemother. 2004. PMID: 15047534 Free PMC article.

5

Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters.

Eustáquio AS, Gust B, Galm U, Li SM, Chater KF, Heide L. Eustáquio AS, et al. Among authors: galm u. Appl Environ Microbiol. 2005 May;71(5):2452-9. doi: 10.1128/AEM.71.5.2452-2459.2005. Appl Environ Microbiol. 2005. PMID: 15870333 Free PMC article.

6

The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892.

Galm U, Wendt-Pienkowski E, Wang L, George NP, Oh TJ, Yi F, Tao M, Coughlin JM, Shen B. Galm U, et al. Mol Biosyst. 2009 Jan;5(1):77-90. doi: 10.1039/b814075h. Epub 2008 Nov 12. Mol Biosyst. 2009. PMID: 19081934 Free PMC article.

7

In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway.

Galm U, Wang L, Wendt-Pienkowski E, Yang R, Liu W, Tao M, Coughlin JM, Shen B. Galm U, et al. J Biol Chem. 2008 Oct 17;283(42):28236-45. doi: 10.1074/jbc.M804971200. Epub 2008 Aug 12. J Biol Chem. 2008. PMID: 18697737 Free PMC article.

8

The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.

Tao M, Wang L, Wendt-Pienkowski E, George NP, Galm U, Zhang G, Coughlin JM, Shen B. Tao M, et al. Among authors: galm u. Mol Biosyst. 2007 Jan;3(1):60-74. doi: 10.1039/b615284h. Epub 2006 Nov 28. Mol Biosyst. 2007. PMID: 17216057

9

Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.

Galm U, Wendt-Pienkowski E, Wang L, Huang SX, Unsin C, Tao M, Coughlin JM, Shen B. Galm U, et al. J Nat Prod. 2011 Mar 25;74(3):526-36. doi: 10.1021/np1008152. Epub 2011 Jan 6. J Nat Prod. 2011. PMID: 21210656 Free PMC article. Review.

10

Natural product drug discovery: the times have never been better.

Galm U, Shen B. Galm U, et al. Chem Biol. 2007 Oct;14(10):1098-104. doi: 10.1016/j.chembiol.2007.10.004. Chem Biol. 2007. PMID: 17961822

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