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Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Fares I, et al. Among authors: iscove nn. Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337. Science. 2014. PMID: 25237102 Free PMC article.
Complementary and independent function for Hoxb4 and Bmi1 in HSC activity.
Faubert A, Chagraoui J, Mayotte N, Fréchette M, Iscove NN, Humphries RK, Sauvageau G. Faubert A, et al. Among authors: iscove nn. Cold Spring Harb Symp Quant Biol. 2008;73:555-64. doi: 10.1101/sqb.2008.73.030. Epub 2008 Nov 6. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19022763
CDK6 levels regulate quiescence exit in human hematopoietic stem cells.
Laurenti E, Frelin C, Xie S, Ferrari R, Dunant CF, Zandi S, Neumann A, Plumb I, Doulatov S, Chen J, April C, Fan JB, Iscove N, Dick JE. Laurenti E, et al. Among authors: iscove n. Cell Stem Cell. 2015 Mar 5;16(3):302-13. doi: 10.1016/j.stem.2015.01.017. Epub 2015 Feb 19. Cell Stem Cell. 2015. PMID: 25704240 Free PMC article.
101 results