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The synthesis of some deoxygenated analogues of early intermediates in the biosynthesis of glycosylphosphatidylinositol (GPI) membrane anchors.
Carbohydr Res. 2004 May 17;339(7):1263-77. doi: 10.1016/j.carres.2004.02.026.
Carbohydr Res. 2004.
PMID: 15113663
Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues.
Smith TK, Sharma DK, Crossman A, Dix A, Brimacombe JS, Ferguson MA.
Smith TK, et al.
EMBO J. 1997 Nov 17;16(22):6667-75. doi: 10.1093/emboj/16.22.6667.
EMBO J. 1997.
PMID: 9362481
Free PMC article.
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Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.
Smith TK, Crossman A, Borissow CN, Paterson MJ, Dix A, Brimacombe JS, Ferguson MA.
Smith TK, et al.
EMBO J. 2001 Jul 2;20(13):3322-32. doi: 10.1093/emboj/20.13.3322.
EMBO J. 2001.
PMID: 11432820
Free PMC article.
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The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.
Ferguson MA, Brimacombe JS, Brown JR, Crossman A, Dix A, Field RA, Güther ML, Milne KG, Sharma DK, Smith TK.
Ferguson MA, et al.
Biochim Biophys Acta. 1999 Oct 8;1455(2-3):327-40. doi: 10.1016/s0925-4439(99)00058-7.
Biochim Biophys Acta. 1999.
PMID: 10571022
Free article.
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