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Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block.
Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, Pradervand S, Evans SM, Clark B, Feramisco JR, Giles W, Ho SY, Benson DW, Silberbach M, Shou W, Chien KR. Pashmforoush M, et al. Among authors: shou w. Cell. 2004 Apr 30;117(3):373-86. doi: 10.1016/s0092-8674(04)00405-2. Cell. 2004. PMID: 15109497 Free article.
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis.
Chen H, Shi S, Acosta L, Li W, Lu J, Bao S, Chen Z, Yang Z, Schneider MD, Chien KR, Conway SJ, Yoder MC, Haneline LS, Franco D, Shou W. Chen H, et al. Among authors: shou w. Development. 2004 May;131(9):2219-31. doi: 10.1242/dev.01094. Epub 2004 Apr 8. Development. 2004. PMID: 15073151 Free PMC article.
Abnormal cardiac development in the absence of heart glycogen.
Pederson BA, Chen H, Schroeder JM, Shou W, DePaoli-Roach AA, Roach PJ. Pederson BA, et al. Among authors: shou w. Mol Cell Biol. 2004 Aug;24(16):7179-87. doi: 10.1128/MCB.24.16.7179-7187.2004. Mol Cell Biol. 2004. PMID: 15282316 Free PMC article.
Notch signaling is essential for ventricular chamber development.
Grego-Bessa J, Luna-Zurita L, del Monte G, Bolós V, Melgar P, Arandilla A, Garratt AN, Zang H, Mukouyama YS, Chen H, Shou W, Ballestar E, Esteller M, Rojas A, Pérez-Pomares JM, de la Pompa JL. Grego-Bessa J, et al. Among authors: shou w. Dev Cell. 2007 Mar;12(3):415-29. doi: 10.1016/j.devcel.2006.12.011. Dev Cell. 2007. PMID: 17336907 Free PMC article.
Smad7 is required for the development and function of the heart.
Chen Q, Chen H, Zheng D, Kuang C, Fang H, Zou B, Zhu W, Bu G, Jin T, Wang Z, Zhang X, Chen J, Field LJ, Rubart M, Shou W, Chen Y. Chen Q, et al. Among authors: shou w. J Biol Chem. 2009 Jan 2;284(1):292-300. doi: 10.1074/jbc.M807233200. Epub 2008 Oct 24. J Biol Chem. 2009. PMID: 18952608 Free PMC article.
305 results