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Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block.
Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, Pradervand S, Evans SM, Clark B, Feramisco JR, Giles W, Ho SY, Benson DW, Silberbach M, Shou W, Chien KR. Pashmforoush M, et al. Among authors: benson dw. Cell. 2004 Apr 30;117(3):373-86. doi: 10.1016/s0092-8674(04)00405-2. Cell. 2004. PMID: 15109497 Free article.
Mouse Model of Human Congenital Heart Disease: Progressive Atrioventricular Block Induced by a Heterozygous Nkx2-5 Homeodomain Missense Mutation.
Chowdhury R, Ashraf H, Melanson M, Tanada Y, Nguyen M, Silberbach M, Wakimoto H, Benson DW, Anderson RH, Kasahara H. Chowdhury R, et al. Among authors: benson dw. Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1255-64. doi: 10.1161/CIRCEP.115.002720. Epub 2015 Jul 30. Circ Arrhythm Electrophysiol. 2015. PMID: 26226998 Free PMC article.
A mouse model of human congenital heart disease: high incidence of diverse cardiac anomalies and ventricular noncompaction produced by heterozygous Nkx2-5 homeodomain missense mutation.
Ashraf H, Pradhan L, Chang EI, Terada R, Ryan NJ, Briggs LE, Chowdhury R, Zárate MA, Sugi Y, Nam HJ, Benson DW, Anderson RH, Kasahara H. Ashraf H, et al. Among authors: benson dw. Circ Cardiovasc Genet. 2014 Aug;7(4):423-433. doi: 10.1161/CIRCGENETICS.113.000281. Epub 2014 Jul 15. Circ Cardiovasc Genet. 2014. PMID: 25028484 Free PMC article.
NKX2.5 mutations in patients with tetralogy of fallot.
Goldmuntz E, Geiger E, Benson DW. Goldmuntz E, et al. Among authors: benson dw. Circulation. 2001 Nov 20;104(21):2565-8. doi: 10.1161/hc4601.098427. Circulation. 2001. PMID: 11714651
324 results