Martín-Caballero J - Search Results

1

Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice.

Espejel S, Martín M, Klatt P, Martín-Caballero J, Flores JM, Blasco MA. Espejel S, et al. EMBO Rep. 2004 May;5(5):503-9. doi: 10.1038/sj.embor.7400127. Epub 2004 Apr 23. EMBO Rep. 2004. PMID: 15105825 Free PMC article.

2

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally.

García-Cao I, García-Cao M, Martín-Caballero J, Criado LM, Klatt P, Flores JM, Weill JC, Blasco MA, Serrano M. García-Cao I, et al. EMBO J. 2002 Nov 15;21(22):6225-35. doi: 10.1093/emboj/cdf595. EMBO J. 2002. PMID: 12426394 Free PMC article.

3

Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice.

Canela A, Martín-Caballero J, Flores JM, Blasco MA. Canela A, et al. Mol Cell Biol. 2004 May;24(10):4275-93. doi: 10.1128/MCB.24.10.4275-4293.2004. Mol Cell Biol. 2004. PMID: 15121848 Free PMC article.

4

Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.

Espejel S, Klatt P, Ménissier-de Murcia J, Martín-Caballero J, Flores JM, Taccioli G, de Murcia G, Blasco MA. Espejel S, et al. J Cell Biol. 2004 Nov 22;167(4):627-38. doi: 10.1083/jcb.200407178. Epub 2004 Nov 15. J Cell Biol. 2004. PMID: 15545322 Free PMC article.

5

Increased p53 activity does not accelerate telomere-driven ageing.

García-Cao I, García-Cao M, Tomás-Loba A, Martín-Caballero J, Flores JM, Klatt P, Blasco MA, Serrano M. García-Cao I, et al. EMBO Rep. 2006 May;7(5):546-52. doi: 10.1038/sj.embor.7400667. Epub 2006 Mar 31. EMBO Rep. 2006. PMID: 16582880 Free PMC article.

6

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres.

Herrera E, Samper E, Martín-Caballero J, Flores JM, Lee HW, Blasco MA. Herrera E, et al. EMBO J. 1999 Jun 1;18(11):2950-60. doi: 10.1093/emboj/18.11.2950. EMBO J. 1999. PMID: 10357808 Free PMC article.

7

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

González-Suárez E, Samper E, Ramírez A, Flores JM, Martín-Caballero J, Jorcano JL, Blasco MA. González-Suárez E, et al. EMBO J. 2001 Jun 1;20(11):2619-30. doi: 10.1093/emboj/20.11.2619. EMBO J. 2001. PMID: 11387197 Free PMC article.

8

Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.

Matheu A, Pantoja C, Efeyan A, Criado LM, Martín-Caballero J, Flores JM, Klatt P, Serrano M. Matheu A, et al. Genes Dev. 2004 Nov 15;18(22):2736-46. doi: 10.1101/gad.310304. Epub 2004 Nov 1. Genes Dev. 2004. PMID: 15520276 Free PMC article.

9

Tumour-suppression activity of the proapoptotic regulator Par4.

García-Cao I, Duran A, Collado M, Carrascosa MJ, Martín-Caballero J, Flores JM, Diaz-Meco MT, Moscat J, Serrano M. García-Cao I, et al. EMBO Rep. 2005 Jun;6(6):577-83. doi: 10.1038/sj.embor.7400421. EMBO Rep. 2005. PMID: 15877079 Free PMC article.

10

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals.

Goytisolo FA, Samper E, Martín-Caballero J, Finnon P, Herrera E, Flores JM, Bouffler SD, Blasco MA. Goytisolo FA, et al. J Exp Med. 2000 Dec 4;192(11):1625-36. doi: 10.1084/jem.192.11.1625. J Exp Med. 2000. PMID: 11104804 Free PMC article.

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