Nebert DW - Search Results

1

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

Uno S, Dalton TP, Sinclair PR, Gorman N, Wang B, Smith AG, Miller ML, Shertzer HG, Nebert DW. Uno S, et al. Among authors: nebert dw. Toxicol Appl Pharmacol. 2004 May 1;196(3):410-21. doi: 10.1016/j.taap.2004.01.014. Toxicol Appl Pharmacol. 2004. PMID: 15094312

2

Dioxin increases reactive oxygen production in mouse liver mitochondria.

Senft AP, Dalton TP, Nebert DW, Genter MB, Hutchinson RJ, Shertzer HG. Senft AP, et al. Among authors: nebert dw. Toxicol Appl Pharmacol. 2002 Jan 1;178(1):15-21. doi: 10.1006/taap.2001.9314. Toxicol Appl Pharmacol. 2002. PMID: 11781075

3

Retrovirally expressed metal response element-binding transcription factor-1 normalizes metallothionein-1 gene expression and protects cells against zinc, but not cadmium, toxicity.

Solis WA, Childs NL, Weedon MN, He L, Nebert DW, Dalton TP. Solis WA, et al. Among authors: nebert dw. Toxicol Appl Pharmacol. 2002 Jan 15;178(2):93-101. doi: 10.1006/taap.2001.9319. Toxicol Appl Pharmacol. 2002. PMID: 11814329

4

Decrease in 4-aminobiphenyl-induced methemoglobinemia in Cyp1a2(-/-) knockout mice.

Shertzer HG, Dalton TP, Talaska G, Nebert DW. Shertzer HG, et al. Among authors: nebert dw. Toxicol Appl Pharmacol. 2002 May 15;181(1):32-7. doi: 10.1006/taap.2002.9398. Toxicol Appl Pharmacol. 2002. PMID: 12030840

5

Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.

Senft AP, Dalton TP, Nebert DW, Genter MB, Puga A, Hutchinson RJ, Kerzee JK, Uno S, Shertzer HG. Senft AP, et al. Among authors: nebert dw. Free Radic Biol Med. 2002 Nov 1;33(9):1268-78. doi: 10.1016/s0891-5849(02)01014-6. Free Radic Biol Med. 2002. PMID: 12398935

6

4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice.

Tsuneoka Y, Dalton TP, Miller ML, Clay CD, Shertzer HG, Talaska G, Medvedovic M, Nebert DW. Tsuneoka Y, et al. Among authors: nebert dw. J Natl Cancer Inst. 2003 Aug 20;95(16):1227-37. doi: 10.1093/jnci/djg025. J Natl Cancer Inst. 2003. PMID: 12928348

7

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.

Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, Nebert DW. Uno S, et al. Among authors: nebert dw. Mol Pharmacol. 2004 May;65(5):1225-37. doi: 10.1124/mol.65.5.1225. Mol Pharmacol. 2004. PMID: 15102951

8

Glutathione redox state regulates mitochondrial reactive oxygen production.

Shen D, Dalton TP, Nebert DW, Shertzer HG. Shen D, et al. Among authors: nebert dw. J Biol Chem. 2005 Jul 8;280(27):25305-12. doi: 10.1074/jbc.M500095200. Epub 2005 May 9. J Biol Chem. 2005. PMID: 15883162 Free article.

9

Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.

Derkenne S, Curran CP, Shertzer HG, Dalton TP, Dragin N, Nebert DW. Derkenne S, et al. Among authors: nebert dw. Pharmacogenet Genomics. 2005 Jul;15(7):503-11. doi: 10.1097/01.fpc.0000167326.00411.50. Pharmacogenet Genomics. 2005. PMID: 15970798

10

Genetic differences in lethality of newborn mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl.

Curran CP, Miller KA, Dalton TP, Vorhees CV, Miller ML, Shertzer HG, Nebert DW. Curran CP, et al. Among authors: nebert dw. Toxicol Sci. 2006 Feb;89(2):454-64. doi: 10.1093/toxsci/kfj048. Epub 2005 Nov 16. Toxicol Sci. 2006. PMID: 16291824

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