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Page 1
N,N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors.
Jia ZJ, Su T, Zuckett JF, Wu Y, Goldman EA, Li W, Zhang P, Clizbe LA, Song Y, Bauer SM, Huang W, Woolfrey J, Sinha U, Arfsten AE, Hutchaleelaha A, Hollenbach SJ, Lambing JL, Scarborough RM, Zhu BY. Jia ZJ, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2004 May 3;14(9):2073-8. doi: 10.1016/j.bmcl.2004.02.049. Bioorg Med Chem Lett. 2004. PMID: 15080981
Design, synthesis, and SAR of substituted acrylamides as factor Xa inhibitors.
Song Y, Clizbe L, Bhakta C, Teng W, Li W, Wu Y, Jia ZJ, Zhang P, Wang L, Doughan B, Su T, Kanter J, Woolfrey J, Wong P, Huang B, Tran K, Sinha U, Park G, Reed A, Malinowski J, Hollenbach S, Scarborough RM, Zhu BY. Song Y, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1511-5. doi: 10.1016/s0960-894x(02)00199-3. Bioorg Med Chem Lett. 2002. PMID: 12031331
Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P(1) structure-activity relationships of the substituted 1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides.
Jia ZJ, Wu Y, Huang W, Goldman E, Zhang P, Woolfrey J, Wong P, Huang B, Sinha U, Park G, Reed A, Scarborough RM, Zhu BY. Jia ZJ, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1651-5. doi: 10.1016/s0960-894x(02)00239-1. Bioorg Med Chem Lett. 2002. PMID: 12039583
Design and synthesis of factor Xa inhibitors and their prodrugs.
Song Y, Clizbe L, Bhakta C, Teng W, Wong P, Huang B, Tran K, Sinha U, Park G, Reed A, Scarborough RM, Zhu BY. Song Y, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2003 Jan 20;13(2):297-300. doi: 10.1016/s0960-894x(02)00921-6. Bioorg Med Chem Lett. 2003. PMID: 12482444
Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors.
Huang W, Zhang P, Zuckett JF, Wang L, Woolfrey J, Song Y, Jia ZJ, Clizbe LA, Su T, Tran K, Huang B, Wong P, Sinha U, Park G, Reed A, Malinowski J, Hollenbach SJ, Scarborough RM, Zhu BY. Huang W, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2003 Feb 10;13(3):561-6. doi: 10.1016/s0960-894x(02)00927-7. Bioorg Med Chem Lett. 2003. PMID: 12565972
95 results