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Page 1
The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity.
Wakasa T, Nonaka K, Harada A, Ohkawa Y, Kikutake C, Suyama M, Kobunai T, Tsunekuni K, Matsuoka K, Kataoka Y, Ochiiwa H, Miyadera K, Sagara T, Oki E, Ohdo S, Maehara Y, Iimori M, Kitao H. Wakasa T, et al. Among authors: kitao h. Cell Death Discov. 2024 Jul 2;10(1):307. doi: 10.1038/s41420-024-02083-3. Cell Death Discov. 2024. PMID: 38956056 Free PMC article.
The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer.
Asanoma K, Yagi H, Onoyama I, Cui L, Hori E, Kawakami M, Maenohara S, Hachisuga K, Tomonobe H, Kodama K, Yasunaga M, Ohgami T, Okugawa K, Yahata H, Kitao H, Kato K. Asanoma K, et al. Among authors: kitao h. J Biol Chem. 2024 Mar;300(3):105695. doi: 10.1016/j.jbc.2024.105695. Epub 2024 Jan 30. J Biol Chem. 2024. PMID: 38301894 Free PMC article.
Mutational spectrum of TP53 gene correlates with nivolumab treatment efficacy in advanced gastric cancer (TP53MUT study).
Ando K, Nakamura Y, Kitao H, Shimokawa M, Kotani D, Bando H, Nishina T, Yamada T, Yuki S, Narita Y, Hara H, Ohta T, Esaki T, Hamamoto Y, Kato K, Yamamoto Y, Minashi K, Ohtsubo K, Izawa N, Kawakami H, Kato T, Satoh T, Okano N, Tsuji A, Yamazaki K, Yoshino T, Maehara Y, Oki E. Ando K, et al. Among authors: kitao h. Br J Cancer. 2023 Oct;129(6):1032-1039. doi: 10.1038/s41416-023-02378-9. Epub 2023 Aug 2. Br J Cancer. 2023. PMID: 37532830 Free PMC article.
Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii.
Maehara Y, Oki E, Ota M, Harimoto N, Ando K, Nakanishi R, Kawazoe T, Fujimoto Y, Nonaka K, Kitao H, Iimori M, Makino K, Takechi T, Sagara T, Miyadera K, Matsuoka K, Tsukihara H, Kataoka Y, Wakasa T, Ochiiwa H, Kamahori Y, Tokunaga E, Saeki H, Yoshizumi T, Kakeji Y, Shirabe K, Baba H, Shimada M. Maehara Y, et al. Among authors: kitao h. Int J Clin Oncol. 2023 May;28(5):613-624. doi: 10.1007/s10147-023-02326-w. Epub 2023 Mar 24. Int J Clin Oncol. 2023. PMID: 36961615
Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2-mutation carriers.
Mori T, Okamoto Y, Mu A, Ide Y, Yoshimura A, Senda N, Inagaki-Kawata Y, Kawashima M, Kitao H, Tokunaga E, Miyoshi Y, Ohsumi S, Tsugawa K, Ohta T, Katagiri T, Ohtsuru S, Koike K, Ogawa S, Toi M, Iwata H, Nakamura S, Matsuo K, Takata M. Mori T, et al. Among authors: kitao h. Cancer Med. 2023 Mar;12(6):6594-6602. doi: 10.1002/cam4.5430. Epub 2022 Nov 7. Cancer Med. 2023. PMID: 36345163 Free PMC article.
Bortezomib-cyclophosphamide-dexamethasone induction/consolidation and bortezomib maintenance for transplant-eligible newly diagnosed multiple myeloma: phase 2 multicenter trial.
Muranushi H, Kanda J, Kobayashi M, Maeda T, Kitano T, Tsuji M, Ueda Y, Ishikawa T, Nohgawa M, Watanabe M, Imada K, Moriguchi T, Itoh M, Ohno H, Yonezawa A, Hirata H, Arima N, Asagoe K, Anzai N, Nagata K, Yasuno S, Kuwabara Y, Kitao H, Kim I, Kawagishi K, Ueshima K, Tominari S, Nakayama T, Yamashita K, Takaori-Kondo A. Muranushi H, et al. Among authors: kitao h. Hematology. 2022 Dec;27(1):239-248. doi: 10.1080/16078454.2022.2032915. Hematology. 2022. PMID: 35152852 Free article. Clinical Trial.
Monitoring FTD in the peripheral blood mononuclear cells of elderly patients with metastatic colorectal cancer administered FTD plus bevacizumab as first-line treatment.
Fujimoto Y, Oki E, Qiu S, Nakanishi R, Makiyama A, Miyamoto Y, Kotaka M, Shimokawa M, Ando K, Kimura Y, Kitao H, Maehara Y, Mori M. Fujimoto Y, et al. Among authors: kitao h. Cancer Sci. 2021 Jun;112(6):2436-2441. doi: 10.1111/cas.14904. Epub 2021 May 3. Cancer Sci. 2021. PMID: 33780084 Free PMC article. Clinical Trial.
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