Stirling DI - Search Results

1

Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.

Shepherd MC, Baillie GS, Stirling DI, Houslay MD. Shepherd MC, et al. Among authors: stirling di. Br J Pharmacol. 2004 May;142(2):339-51. doi: 10.1038/sj.bjp.0705770. Epub 2004 Apr 5. Br J Pharmacol. 2004. PMID: 15066910 Free PMC article.

2

Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.

Schafer PH, Parton A, Gandhi AK, Capone L, Adams M, Wu L, Bartlett JB, Loveland MA, Gilhar A, Cheung YF, Baillie GS, Houslay MD, Man HW, Muller GW, Stirling DI. Schafer PH, et al. Among authors: stirling di. Br J Pharmacol. 2010 Feb;159(4):842-55. doi: 10.1111/j.1476-5381.2009.00559.x. Epub 2009 Dec 24. Br J Pharmacol. 2010. PMID: 20050849 Free PMC article.

3

Thalidomide analogs and PDE4 inhibition.

Muller GW, Shire MG, Wong LM, Corral LG, Patterson RT, Chen Y, Stirling DI. Muller GW, et al. Among authors: stirling di. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2669-74. doi: 10.1016/s0960-894x(98)00475-2. Bioorg Med Chem Lett. 1998. PMID: 9873600

4

Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues.

Prehn JL, Landers C, Muller GW, Man HW, Stirling DI, Targan SR. Prehn JL, et al. Among authors: stirling di. J Clin Immunol. 2001 Sep;21(5):357-64. doi: 10.1023/a:1012292703871. J Clin Immunol. 2001. PMID: 11720008

5

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects.

Dredge K, Marriott JB, Macdonald CD, Man HW, Chen R, Muller GW, Stirling D, Dalgleish AG. Dredge K, et al. Br J Cancer. 2002 Nov 4;87(10):1166-72. doi: 10.1038/sj.bjc.6600607. Br J Cancer. 2002. PMID: 12402158 Free PMC article.

6

Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.

Schafer PH, Parton A, Capone L, Cedzik D, Brady H, Evans JF, Man HW, Muller GW, Stirling DI, Chopra R. Schafer PH, et al. Among authors: stirling di. Cell Signal. 2014 Sep;26(9):2016-29. doi: 10.1016/j.cellsig.2014.05.014. Epub 2014 May 29. Cell Signal. 2014. PMID: 24882690 Free article.

7

Recent clinical studies of the immunomodulatory drug (IMiD) lenalidomide.

Bartlett JB, Tozer A, Stirling D, Zeldis JB. Bartlett JB, et al. Br J Cancer. 2005 Sep 19;93(6):613-9. doi: 10.1038/sj.bjc.6602774. Br J Cancer. 2005. PMID: 16222306 Free PMC article. Review.

8

Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-alpha inhibitor.

Man HW, Schafer P, Wong LM, Patterson RT, Corral LG, Raymon H, Blease K, Leisten J, Shirley MA, Tang Y, Babusis DM, Chen R, Stirling D, Muller GW. Man HW, et al. J Med Chem. 2009 Mar 26;52(6):1522-4. doi: 10.1021/jm900210d. J Med Chem. 2009. PMID: 19256507

9

lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells.

Wu L, Adams M, Carter T, Chen R, Muller G, Stirling D, Schafer P, Bartlett JB. Wu L, et al. Clin Cancer Res. 2008 Jul 15;14(14):4650-7. doi: 10.1158/1078-0432.CCR-07-4405. Clin Cancer Res. 2008. PMID: 18628480

10

Immunomodulatory drugs inhibit expression of cyclooxygenase-2 from TNF-alpha, IL-1beta, and LPS-stimulated human PBMC in a partially IL-10-dependent manner.

Payvandi F, Wu L, Haley M, Schafer PH, Zhang LH, Chen RS, Muller GW, Stirling DI. Payvandi F, et al. Among authors: stirling di. Cell Immunol. 2004 Aug;230(2):81-8. doi: 10.1016/j.cellimm.2004.09.003. Cell Immunol. 2004. PMID: 15598423

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

83 results

Search Page

Filters