Cerebrospinal fluid ceftazidime kinetics in patients with external ventriculostomies.
Nau R, Prange HW, Kinzig M, Frank A, Dressel A, Scholz P, Kolenda H, Sörgel F.
Nau R, et al. Among authors: kolenda h.
Antimicrob Agents Chemother. 1996 Mar;40(3):763-6. doi: 10.1128/AAC.40.3.763.
Antimicrob Agents Chemother. 1996.
PMID: 8851607
Free PMC article.
Clinical Trial.
The elimination half-lives were 3.13 to 18.1 h (median, 10.7 h) in CSF compared with 2.02 to 5.24 h (median, 3.74 h) in serum. The ratios of the areas under the concentration-time curves in CSF and serum (AUCCSF/AUCS) ranged from 0.027 to 0.123 (median …
The elimination half-lives were 3.13 to 18.1 h (median, 10.7 h) in CSF compared with 2.02 to 5.24 h (median, 3.74 h …