Salvesen GS - Search Results

1

Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases.

Ekici OD, Götz MG, James KE, Li ZZ, Rukamp BJ, Asgian JL, Caffrey CR, Hansell E, Dvorák J, McKerrow JH, Potempa J, Travis J, Mikolajczyk J, Salvesen GS, Powers JC. Ekici OD, et al. Among authors: salvesen gs. J Med Chem. 2004 Apr 8;47(8):1889-92. doi: 10.1021/jm049938j. J Med Chem. 2004. PMID: 15055989

2

Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10.

Ekici OD, Li ZZ, Campbell AJ, James KE, Asgian JL, Mikolajczyk J, Salvesen GS, Ganesan R, Jelakovic S, Grütter MG, Powers JC. Ekici OD, et al. Among authors: salvesen gs. J Med Chem. 2006 Sep 21;49(19):5728-49. doi: 10.1021/jm0601405. J Med Chem. 2006. PMID: 16970398

3

Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases.

Asgian JL, James KE, Li ZZ, Carter W, Barrett AJ, Mikolajczyk J, Salvesen GS, Powers JC. Asgian JL, et al. Among authors: salvesen gs. J Med Chem. 2002 Nov 7;45(23):4958-60. doi: 10.1021/jm025581c. J Med Chem. 2002. PMID: 12408706

4

Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1, -3, -6, and -8.

James KE, Asgian JL, Li ZZ, Ekici OD, Rubin JR, Mikolajczyk J, Salvesen GS, Powers JC. James KE, et al. Among authors: salvesen gs. J Med Chem. 2004 Mar 11;47(6):1553-74. doi: 10.1021/jm0305016. J Med Chem. 2004. PMID: 14998341

5

Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors.

Corrigan TS, Lotti Diaz LM, Border SE, Ratigan SC, Kasper KQ, Sojka D, Fajtova P, Caffrey CR, Salvesen GS, McElroy CA, Hadad CM, Doğan Ekici Ö. Corrigan TS, et al. Among authors: salvesen gs. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1387-1402. doi: 10.1080/14756366.2020.1781107. J Enzyme Inhib Med Chem. 2020. PMID: 32633155 Free PMC article.

6

Sequential autolytic processing activates the zymogen of Arg-gingipain.

Mikolajczyk J, Boatright KM, Stennicke HR, Nazif T, Potempa J, Bogyo M, Salvesen GS. Mikolajczyk J, et al. Among authors: salvesen gs. J Biol Chem. 2003 Mar 21;278(12):10458-64. doi: 10.1074/jbc.M210564200. Epub 2003 Jan 17. J Biol Chem. 2003. PMID: 12533545 Free article.

7

Molecular cloning of human neutrophil elastase.

Farley D, Salvesen G, Travis J. Farley D, et al. Biol Chem Hoppe Seyler. 1988 May;369 Suppl:3-7. Biol Chem Hoppe Seyler. 1988. PMID: 2462434

8

The human neutrophil elastase gene. Analysis of the nucleotide sequence reveals three distinct classes of repetitive DNA.

Farley D, Travis J, Salvesen G. Farley D, et al. Biol Chem Hoppe Seyler. 1989 Jul;370(7):737-44. doi: 10.1515/bchm3.1989.370.2.737. Biol Chem Hoppe Seyler. 1989. PMID: 2775493

9

Inhibition of distant caspase homologues by natural caspase inhibitors.

Snipas SJ, Stennicke HR, Riedl S, Potempa J, Travis J, Barrett AJ, Salvesen GS. Snipas SJ, et al. Among authors: salvesen gs. Biochem J. 2001 Jul 15;357(Pt 2):575-80. doi: 10.1042/0264-6021:3570575. Biochem J. 2001. PMID: 11439111 Free PMC article.

10

Neutrophil elastase and cathepsin G: structure, function, and biological control.

Watorek W, Farley D, Salvesen G, Travis J. Watorek W, et al. Adv Exp Med Biol. 1988;240:23-31. doi: 10.1007/978-1-4613-1057-0_3. Adv Exp Med Biol. 1988. PMID: 3266707

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