Ekici OD - Search Results

1

Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases.

Ekici OD, Götz MG, James KE, Li ZZ, Rukamp BJ, Asgian JL, Caffrey CR, Hansell E, Dvorák J, McKerrow JH, Potempa J, Travis J, Mikolajczyk J, Salvesen GS, Powers JC. Ekici OD, et al. J Med Chem. 2004 Apr 8;47(8):1889-92. doi: 10.1021/jm049938j. J Med Chem. 2004. PMID: 15055989

2

Irreversible inhibitors of serine, cysteine, and threonine proteases.

Powers JC, Asgian JL, Ekici OD, James KE. Powers JC, et al. Among authors: ekici od. Chem Rev. 2002 Dec;102(12):4639-750. doi: 10.1021/cr010182v. Chem Rev. 2002. PMID: 12475205 Review. No abstract available.

3

Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1, -3, -6, and -8.

James KE, Asgian JL, Li ZZ, Ekici OD, Rubin JR, Mikolajczyk J, Salvesen GS, Powers JC. James KE, et al. Among authors: ekici od. J Med Chem. 2004 Mar 11;47(6):1553-74. doi: 10.1021/jm0305016. J Med Chem. 2004. PMID: 14998341

4

Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10.

Ekici OD, Li ZZ, Campbell AJ, James KE, Asgian JL, Mikolajczyk J, Salvesen GS, Ganesan R, Jelakovic S, Grütter MG, Powers JC. Ekici OD, et al. J Med Chem. 2006 Sep 21;49(19):5728-49. doi: 10.1021/jm0601405. J Med Chem. 2006. PMID: 16970398

5

Demonstration of In Vitro Resurrection of Aged Acetylcholinesterase after Exposure to Organophosphorus Chemical Nerve Agents.

Zhuang Q, Franjesevic AJ, Corrigan TS, Coldren WH, Dicken R, Sillart S, DeYong A, Yoshino N, Smith J, Fabry S, Fitzpatrick K, Blanton TG, Joseph J, Yoder RJ, McElroy CA, Ekici ÖD, Callam CS, Hadad CM. Zhuang Q, et al. Among authors: ekici od. J Med Chem. 2018 Aug 23;61(16):7034-7042. doi: 10.1021/acs.jmedchem.7b01620. Epub 2018 Jun 20. J Med Chem. 2018. PMID: 29870665

6

Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration.

Ekici OD, Paetzel M, Dalbey RE. Ekici OD, et al. Protein Sci. 2008 Dec;17(12):2023-37. doi: 10.1110/ps.035436.108. Epub 2008 Sep 29. Protein Sci. 2008. PMID: 18824507 Free PMC article. Review.

7

Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase.

Zhuang Q, Young A, Callam CS, McElroy CA, Ekici ÖD, Yoder RJ, Hadad CM. Zhuang Q, et al. Among authors: ekici od. Ann N Y Acad Sci. 2016 Jun;1374(1):94-104. doi: 10.1111/nyas.13124. Epub 2016 Jun 21. Ann N Y Acad Sci. 2016. PMID: 27327269 Free PMC article. Review.

8

Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library.

Ekici OD, Karla A, Paetzel M, Lively MO, Pei D, Dalbey RE. Ekici OD, et al. J Biol Chem. 2007 Jan 5;282(1):417-25. doi: 10.1074/jbc.M608779200. Epub 2006 Oct 31. J Biol Chem. 2007. PMID: 17077081 Free article.

9

Signal Peptidase Enzymology and Substrate Specificity Profiling.

Dalbey RE, Pei D, Ekici ÖD. Dalbey RE, et al. Among authors: ekici od. Methods Enzymol. 2017;584:35-57. doi: 10.1016/bs.mie.2016.09.025. Epub 2016 Oct 21. Methods Enzymol. 2017. PMID: 28065271 Review.

10

Profiling the substrate specificity of viral protease VP4 by a FRET-based peptide library approach.

Ekici OD, Zhu J, Wah Chung IY, Paetzel M, Dalbey RE, Pei D. Ekici OD, et al. Biochemistry. 2009 Jun 23;48(24):5753-9. doi: 10.1021/bi900461e. Biochemistry. 2009. PMID: 19435306

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