Hansen HP - Search Results

1

The ectodomain shedding of CD30 is specifically regulated by peptide motifs in its cysteine-rich domains 2 and 5.

Hansen HP, Recke A, Reineke U, Von Tresckow B, Borchmann P, Von Strandmann EP, Lange H, Lemke H, Engert A. Hansen HP, et al. FASEB J. 2004 May;18(7):893-5. doi: 10.1096/fj.03-0901fje. Epub 2004 Mar 19. FASEB J. 2004. PMID: 15033921

2

Combination of the human anti-CD30 antibody 5F11 with cytostatic drugs enhances its antitumor activity against Hodgkin and anaplastic large cell lymphoma cell lines.

Heuck F, Ellermann J, Borchmann P, Rothe A, Hansen H, Engert A, von Strandmann EP. Heuck F, et al. J Immunother. 2004 Sep-Oct;27(5):347-53. doi: 10.1097/00002371-200409000-00003. J Immunother. 2004. PMID: 15314543

3

Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

von Tresckow B, Kallen KJ, von Strandmann EP, Borchmann P, Lange H, Engert A, Hansen HP. von Tresckow B, et al. Among authors: hansen hp. J Immunol. 2004 Apr 1;172(7):4324-31. doi: 10.4049/jimmunol.172.7.4324. J Immunol. 2004. PMID: 15034047

4

ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro.

Eichenauer DA, Simhadri VL, von Strandmann EP, Ludwig A, Matthews V, Reiners KS, von Tresckow B, Saftig P, Rose-John S, Engert A, Hansen HP. Eichenauer DA, et al. Among authors: hansen hp. Cancer Res. 2007 Jan 1;67(1):332-8. doi: 10.1158/0008-5472.CAN-06-2470. Cancer Res. 2007. PMID: 17210715

5

TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species.

Vahdat AM, Reiners KS, Simhadri VL, Eichenauer DA, Böll B, Chalaris A, Simhadri VR, Wiegmann K, Krell HW, Rose-John S, Engert A, von Strandmann EP, Hansen HP. Vahdat AM, et al. Among authors: hansen hp. Leukemia. 2010 Jan;24(1):51-7. doi: 10.1038/leu.2009.230. Epub 2009 Nov 5. Leukemia. 2010. PMID: 19890373

6

A Phase I study with an anti-CD30 ricin A-chain immunotoxin (Ki-4.dgA) in patients with refractory CD30+ Hodgkin's and non-Hodgkin's lymphoma.

Schnell R, Staak O, Borchmann P, Schwartz C, Matthey B, Hansen H, Schindler J, Ghetie V, Vitetta ES, Diehl V, Engert A. Schnell R, et al. Clin Cancer Res. 2002 Jun;8(6):1779-86. Clin Cancer Res. 2002. PMID: 12060617 Clinical Trial.

7

The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma.

Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A. Borchmann P, et al. Blood. 2003 Nov 15;102(10):3737-42. doi: 10.1182/blood-2003-02-0515. Epub 2003 Jul 24. Blood. 2003. PMID: 12881320 Free article.

8

The fully human anti-CD30 antibody 5F11 activates NF-{kappa}B and sensitizes lymphoma cells to bortezomib-induced apoptosis.

Böll B, Hansen H, Heuck F, Reiners K, Borchmann P, Rothe A, Engert A, Pogge von Strandmann E. Böll B, et al. Blood. 2005 Sep 1;106(5):1839-42. doi: 10.1182/blood-2005-01-0427. Epub 2005 May 5. Blood. 2005. PMID: 15878978 Free article.

9

Treatment of refractory Hodgkin's lymphoma patients with an iodine-131-labeled murine anti-CD30 monoclonal antibody.

Schnell R, Dietlein M, Staak JO, Borchmann P, Schomaecker K, Fischer T, Eschner W, Hansen H, Morschhauser F, Schicha H, Diehl V, Raubitschek A, Engert A. Schnell R, et al. J Clin Oncol. 2005 Jul 20;23(21):4669-78. doi: 10.1200/JCO.2005.09.098. J Clin Oncol. 2005. PMID: 16034043

10

Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin.

Hansen HP, Matthey B, Barth S, Kisseleva T, Mokros T, Davies SJ, Beckett RP, Foelster-Holst R, Lange HH, Engert A, Lemke H. Hansen HP, et al. Int J Cancer. 2002 Mar 10;98(2):210-5. doi: 10.1002/ijc.10182. Int J Cancer. 2002. PMID: 11857410

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