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Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.
Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Zabolotny JM, et al. Among authors: neel bg. J Biol Chem. 2004 Jun 4;279(23):24844-51. doi: 10.1074/jbc.M310688200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15031294 Free article.
PTP1B regulates leptin signal transduction in vivo.
Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, Neel BG. Zabolotny JM, et al. Among authors: neel bg. Dev Cell. 2002 Apr;2(4):489-95. doi: 10.1016/s1534-5807(02)00148-x. Dev Cell. 2002. PMID: 11970898 Free article.
Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues.
Xue B, Pulinilkunnil T, Murano I, Bence KK, He H, Minokoshi Y, Asakura K, Lee A, Haj F, Furukawa N, Catalano KJ, Delibegovic M, Balschi JA, Cinti S, Neel BG, Kahn BB. Xue B, et al. Among authors: neel bg. Mol Cell Biol. 2009 Aug;29(16):4563-73. doi: 10.1128/MCB.01914-08. Epub 2009 Jun 15. Mol Cell Biol. 2009. PMID: 19528236 Free PMC article.
307 results