Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos.
Sutovsky P, Moreno RD, Ramalho-Santos J, Dominko T, Simerly C, Schatten G.
Sutovsky P, et al.
Biol Reprod. 2000 Aug;63(2):582-90. doi: 10.1095/biolreprod63.2.582.
Biol Reprod. 2000.
PMID: 10906068
We have recently reported that the sperm mitochondria are ubiquitinated inside the oocyte cytoplasm and later subjected to proteolysis during preimplantation development (P. Sutovsky et al., Nature 1999; 402:371-372). Here, we provide further evidence for this proce …
We have recently reported that the sperm mitochondria are ubiquitinated inside the oocyte cytoplasm and later subjected to proteolysis durin …