Smith RL - Search Results

1

Thieno[2,3-b]furan-2-sulfonamides as topical carbonic anhydrase inhibitors.

Hartman GD, Halczenko W, Prugh JD, Smith RL, Sugrue MF, Mallorga P, Michelson SR, Randall WC, Schwam H, Sondey JM. Hartman GD, et al. Among authors: smith rl. J Med Chem. 1992 Aug 7;35(16):3027-33. doi: 10.1021/jm00094a016. J Med Chem. 1992. PMID: 1501230

2

Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides.

Shepard KL, Graham SL, Hudcosky RJ, Michelson SR, Scholz TH, Schwam H, Smith AM, Sondey JM, Strohmaier KM, Smith RL, et al. Shepard KL, et al. Among authors: smith am, smith rl. J Med Chem. 1991 Oct;34(10):3098-105. doi: 10.1021/jm00114a020. J Med Chem. 1991. PMID: 1920359

3

New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides.

Prugh JD, Hartman GD, Mallorga PJ, McKeever BM, Michelson SR, Murcko MA, Schwam H, Smith RL, Sondey JM, Springer JP, et al. Prugh JD, et al. Among authors: smith rl. J Med Chem. 1991 Jun;34(6):1805-18. doi: 10.1021/jm00110a008. J Med Chem. 1991. PMID: 2061922

4

L-662,583 is a topically effective ocular hypotensive carbonic anhydrase inhibitor in experimental animals.

Sugrue MF, Gautheron P, Mallorga P, Nolan TE, Graham SL, Schwam H, Shepard KL, Smith RL. Sugrue MF, et al. Among authors: smith rl. Br J Pharmacol. 1990 Jan;99(1):59-64. doi: 10.1111/j.1476-5381.1990.tb14654.x. Br J Pharmacol. 1990. PMID: 2110013 Free PMC article.

5

Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides.

Graham SL, Hoffman JM, Gautheron P, Michelson SR, Scholz TH, Schwam H, Shepard KL, Smith AM, Smith RL, Sondey JM, et al. Graham SL, et al. Among authors: smith am, smith rl. J Med Chem. 1990 Feb;33(2):749-54. doi: 10.1021/jm00164a045. J Med Chem. 1990. PMID: 2299640

6

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 6. Trans-6-[2-(substituted-1-naphthyl)ethyl(or ethenyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones.

Prugh JD, Alberts AW, Deana AA, Gilfillian JL, Huff JW, Smith RL, Wiggins JM. Prugh JD, et al. Among authors: smith rl. J Med Chem. 1990 Feb;33(2):758-65. doi: 10.1021/jm00164a047. J Med Chem. 1990. PMID: 2299642

7

3-substituted thieno[2,3-b][1,4]thiazine-6-sulfonamides. A novel class of topically active carbonic anhydrase inhibitors.

Hunt CA, Mallorga PJ, Michelson SR, Schwam H, Sondey JM, Smith RL, Sugrue MF, Shepard KL. Hunt CA, et al. Among authors: smith rl. J Med Chem. 1994 Jan 21;37(2):240-7. doi: 10.1021/jm00028a006. J Med Chem. 1994. PMID: 8295211

8

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs.

Hartman GD, Halczenko W, Duggan ME, Imagire JS, Smith RL, Pitzenberger SM, Fitzpatrick SL, Alberts AW, Bostedor R, Chao YS, et al. Hartman GD, et al. Among authors: smith rl. J Med Chem. 1992 Oct 16;35(21):3813-21. doi: 10.1021/jm00099a009. J Med Chem. 1992. PMID: 1433193

9

4-substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors.

Hartman GD, Halczenko W, Smith RL, Sugŕue MF, Mallorga PJ, Michelson SR, Randall WC, Schwam H, Sondey JM. Hartman GD, et al. Among authors: smith rl. J Med Chem. 1992 Oct 16;35(21):3822-31. doi: 10.1021/jm00099a010. J Med Chem. 1992. PMID: 1433194

10

Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors.

Hartman GD, Egbertson MS, Halczenko W, Laswell WL, Duggan ME, Smith RL, Naylor AM, Manno PD, Lynch RJ, Zhang G, et al. Hartman GD, et al. Among authors: smith rl. J Med Chem. 1992 Nov 27;35(24):4640-2. doi: 10.1021/jm00102a020. J Med Chem. 1992. PMID: 1469694 No abstract available.

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