Hartman GD - Search Results

1

Thieno[2,3-b]furan-2-sulfonamides as topical carbonic anhydrase inhibitors.

Hartman GD, Halczenko W, Prugh JD, Smith RL, Sugrue MF, Mallorga P, Michelson SR, Randall WC, Schwam H, Sondey JM. Hartman GD, et al. J Med Chem. 1992 Aug 7;35(16):3027-33. doi: 10.1021/jm00094a016. J Med Chem. 1992. PMID: 1501230

2

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs.

Hartman GD, Halczenko W, Duggan ME, Imagire JS, Smith RL, Pitzenberger SM, Fitzpatrick SL, Alberts AW, Bostedor R, Chao YS, et al. Hartman GD, et al. J Med Chem. 1992 Oct 16;35(21):3813-21. doi: 10.1021/jm00099a009. J Med Chem. 1992. PMID: 1433193

3

4-substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors.

Hartman GD, Halczenko W, Smith RL, Sugŕue MF, Mallorga PJ, Michelson SR, Randall WC, Schwam H, Sondey JM. Hartman GD, et al. J Med Chem. 1992 Oct 16;35(21):3822-31. doi: 10.1021/jm00099a010. J Med Chem. 1992. PMID: 1433194

4

Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors.

Hartman GD, Egbertson MS, Halczenko W, Laswell WL, Duggan ME, Smith RL, Naylor AM, Manno PD, Lynch RJ, Zhang G, et al. Hartman GD, et al. J Med Chem. 1992 Nov 27;35(24):4640-2. doi: 10.1021/jm00102a020. J Med Chem. 1992. PMID: 1469694 No abstract available.

5

New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides.

Prugh JD, Hartman GD, Mallorga PJ, McKeever BM, Michelson SR, Murcko MA, Schwam H, Smith RL, Sondey JM, Springer JP, et al. Prugh JD, et al. Among authors: hartman gd. J Med Chem. 1991 Jun;34(6):1805-18. doi: 10.1021/jm00110a008. J Med Chem. 1991. PMID: 2061922

6

Non-peptide fibrinogen receptor antagonists. 2. Optimization of a tyrosine template as a mimic for Arg-Gly-Asp.

Egbertson MS, Chang CT, Duggan ME, Gould RJ, Halczenko W, Hartman GD, Laswell WL, Lynch JJ Jr, Lynch RJ, Manno PD, et al. Egbertson MS, et al. Among authors: hartman gd. J Med Chem. 1994 Aug 5;37(16):2537-51. doi: 10.1021/jm00042a007. J Med Chem. 1994. PMID: 8057299

7

Non-peptide glycoprotein IIb/IIIa antagonists. 11. Design and in vivo evaluation of 3,4-dihydro-1 (1H)-isoquinolinone-based antagonists and ethyl ester prodrugs.

Hutchinson JH, Cook JJ, Brashear KM, Breslin MJ, Glass JD, Gould RJ, Halczenko W, Holahan MA, Lynch RJ, Sitko GR, Stranieri MT, Hartman GD. Hutchinson JH, et al. Among authors: hartman gd. J Med Chem. 1996 Nov 8;39(23):4583-91. doi: 10.1021/jm9604787. J Med Chem. 1996. PMID: 8917647

8

Non-peptide GPIIb/IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation.

Egbertson MS, Cook JJ, Bednar B, Prugh JD, Bednar RA, Gaul SL, Gould RJ, Hartman GD, Homnick CF, Holahan MA, Libby LA, Lynch JJ Jr, Lynch RJ, Sitko GR, Stranieri MT, Vassallo LM. Egbertson MS, et al. Among authors: hartman gd. J Med Chem. 1999 Jul 1;42(13):2409-21. doi: 10.1021/jm980722p. J Med Chem. 1999. PMID: 10395482

9

Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis.

Hutchinson JH, Halczenko W, Brashear KM, Breslin MJ, Coleman PJ, Duong LT, Fernandez-Metzler C, Gentile MA, Fisher JE, Hartman GD, Huff JR, Kimmel DB, Leu CT, Meissner RS, Merkle K, Nagy R, Pennypacker B, Perkins JJ, Prueksaritanont T, Rodan GA, Varga SL, Wesolowski GA, Zartman AE, Rodan SB, Duggan ME. Hutchinson JH, et al. Among authors: hartman gd. J Med Chem. 2003 Oct 23;46(22):4790-8. doi: 10.1021/jm030306r. J Med Chem. 2003. PMID: 14561098

10

3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. 7. Modification of the hexahydronaphthalene moiety of simvastatin: 5-oxygenated and 5-oxa derivatives.

Duggan ME, Alberts AW, Bostedor R, Chao YS, Germershausen JI, Gilfillan JL, Halczenko W, Hartman GD, Hunt V, Imagire JS, et al. Duggan ME, et al. Among authors: hartman gd. J Med Chem. 1991 Aug;34(8):2489-95. doi: 10.1021/jm00112a027. J Med Chem. 1991. PMID: 1875346

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