Mistry P - Search Results

1

Studies on pyrrolopyrimidines as selective inhibitors of multidrug-resistance-associated protein in multidrug resistance.

Wang S, Folkes A, Chuckowree I, Cockcroft X, Sohal S, Miller W, Milton J, Wren SP, Vicker N, Depledge P, Scott J, Smith L, Jones H, Mistry P, Faint R, Thompson D, Cocks S. Wang S, et al. Among authors: mistry p. J Med Chem. 2004 Mar 11;47(6):1329-38. doi: 10.1021/jm031011g. J Med Chem. 2004. PMID: 14998323

2

Novel angular benzophenazines: dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents.

Vicker N, Burgess L, Chuckowree IS, Dodd R, Folkes AJ, Hardick DJ, Hancox TC, Miller W, Milton J, Sohal S, Wang S, Wren SP, Charlton PA, Dangerfield W, Liddle C, Mistry P, Stewart AJ, Denny WA. Vicker N, et al. Among authors: mistry p. J Med Chem. 2002 Jan 31;45(3):721-39. doi: 10.1021/jm010329a. J Med Chem. 2002. PMID: 11806724

3

Structure-activity relationships for analogues of the phenazine-based dual topoisomerase I/II inhibitor XR11576.

Wang S, Miller W, Milton J, Vicker N, Stewart A, Charlton P, Mistry P, Hardick D, Denny WA. Wang S, et al. Among authors: mistry p. Bioorg Med Chem Lett. 2002 Feb 11;12(3):415-8. doi: 10.1016/s0960-894x(01)00770-3. Bioorg Med Chem Lett. 2002. PMID: 11814810

4

Design and synthesis of new templates derived from pyrrolopyrimidine as selective multidrug-resistance-associated protein inhibitors in multidrug resistance.

Wang S, Wan NC, Harrison J, Miller W, Chuckowree I, Sohal S, Hancox TC, Baker S, Folkes A, Wilson F, Thompson D, Cocks S, Farmer H, Boyce A, Freathy C, Broadbridge J, Scott J, Depledge P, Faint R, Mistry P, Charlton P. Wang S, et al. Among authors: mistry p. J Med Chem. 2004 Mar 11;47(6):1339-50. doi: 10.1021/jm0310129. J Med Chem. 2004. PMID: 14998324

5

Structure-activity relationships for pyrido-, imidazo-, pyrazolo-, pyrazino-, and pyrrolophenazinecarboxamides as topoisomerase-targeted anticancer agents.

Gamage SA, Spicer JA, Rewcastle GW, Milton J, Sohal S, Dangerfield W, Mistry P, Vicker N, Charlton PA, Denny WA. Gamage SA, et al. Among authors: mistry p. J Med Chem. 2002 Jan 31;45(3):740-3. doi: 10.1021/jm010330+. J Med Chem. 2002. PMID: 11806725

6

ONT-093 (Ontogen).

Mistry P, Folkes A. Mistry P, et al. Curr Opin Investig Drugs. 2002 Nov;3(11):1666-71. Curr Opin Investig Drugs. 2002. PMID: 12476971 Review.

7

Preclinical anti-tumor activity of XR5944 in combination with carboplatin or doxorubicin in non-small-cell lung carcinoma.

Harris SM, Scott JA, Brown JL, Charlton PA, Mistry P. Harris SM, et al. Among authors: mistry p. Anticancer Drugs. 2005 Oct;16(9):945-51. doi: 10.1097/01.cad.0000176499.17939.56. Anticancer Drugs. 2005. PMID: 16162971

8

4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase.

Alexander R, Balasundaram A, Batchelor M, Brookings D, Crépy K, Crabbe T, Deltent MF, Driessens F, Gill A, Harris S, Hutchinson G, Kulisa C, Merriman M, Mistry P, Parton T, Turner J, Whitcombe I, Wright S. Alexander R, et al. Among authors: mistry p. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4316-20. doi: 10.1016/j.bmcl.2008.06.076. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18625552

9

In vivo efficacy of XR9051, a potent modulator of P-glycoprotein mediated multidrug resistance.

Mistry P, Plumb J, Eccles S, Watson S, Dale I, Ryder H, Box G, Charlton P, Templeton D, Bevan PB. Mistry P, et al. Br J Cancer. 1999 Apr;79(11-12):1672-8. doi: 10.1038/sj.bjc.6690267. Br J Cancer. 1999. PMID: 10206276 Free PMC article.

10

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

Mistry P, Stewart AJ, Dangerfield W, Okiji S, Liddle C, Bootle D, Plumb JA, Templeton D, Charlton P. Mistry P, et al. Cancer Res. 2001 Jan 15;61(2):749-58. Cancer Res. 2001. PMID: 11212278

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