Holmes DJ - Search Results

1

Validation of antibacterial mechanism of action using regulated antisense RNA expression in Staphylococcus aureus.

Ji Y, Yin D, Fox B, Holmes DJ, Payne D, Rosenberg M. Ji Y, et al. Among authors: holmes dj. FEMS Microbiol Lett. 2004 Feb 16;231(2):177-84. doi: 10.1016/S0378-1097(03)00931-5. FEMS Microbiol Lett. 2004. PMID: 14987762

2

Identification of antimicrobial targets using a comprehensive genomic approach.

Yin D, Fox B, Lonetto ML, Etherton MR, Payne DJ, Holmes DJ, Rosenberg M, Ji Y. Yin D, et al. Among authors: holmes dj. Pharmacogenomics. 2004 Jan;5(1):101-13. doi: 10.1517/phgs.5.1.101.25679. Pharmacogenomics. 2004. PMID: 14683422

3

Novel targets for the future development of antibacterial agents.

McDevitt D, Payne DJ, Holmes DJ, Rosenberg M. McDevitt D, et al. Among authors: holmes dj. J Appl Microbiol. 2002;92 Suppl:28S-34S. J Appl Microbiol. 2002. PMID: 12000610 Review.

4

Novel targets for the future development of antibacterial agents.

McDevitt D, Payne DJ, Holmes DJ, Rosenberg M. McDevitt D, et al. Among authors: holmes dj. Symp Ser Soc Appl Microbiol. 2002;(31):28S-34S. Symp Ser Soc Appl Microbiol. 2002. PMID: 12481826 Review.

5

Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK).

Marrakchi H, Dewolf WE Jr, Quinn C, West J, Polizzi BJ, So CY, Holmes DJ, Reed SL, Heath RJ, Payne DJ, Rock CO, Wallis NG. Marrakchi H, et al. Among authors: holmes dj. Biochem J. 2003 Mar 15;370(Pt 3):1055-62. doi: 10.1042/BJ20021699. Biochem J. 2003. PMID: 12487627 Free PMC article.

6

Genomic approaches to antibacterial discovery.

Payne DJ, Gwynn MN, Holmes DJ, Rosenberg M. Payne DJ, et al. Among authors: holmes dj. Methods Mol Biol. 2004;266:231-59. doi: 10.1385/1-59259-763-7:231. Methods Mol Biol. 2004. PMID: 15148422

7

Drugs for bad bugs: confronting the challenges of antibacterial discovery.

Payne DJ, Gwynn MN, Holmes DJ, Pompliano DL. Payne DJ, et al. Among authors: holmes dj. Nat Rev Drug Discov. 2007 Jan;6(1):29-40. doi: 10.1038/nrd2201. Epub 2006 Dec 8. Nat Rev Drug Discov. 2007. PMID: 17159923 Review.

8

Delivering novel targets and antibiotics from genomics.

Payne DJ, Holmes DJ, Rosenberg M. Payne DJ, et al. Among authors: holmes dj. Curr Opin Investig Drugs. 2001 Aug;2(8):1028-34. Curr Opin Investig Drugs. 2001. PMID: 11892909 Review.

9

Characterization of a novel fucose-regulated promoter (PfcsK) suitable for gene essentiality and antibacterial mode-of-action studies in Streptococcus pneumoniae.

Chan PF, O'Dwyer KM, Palmer LM, Ambrad JD, Ingraham KA, So C, Lonetto MA, Biswas S, Rosenberg M, Holmes DJ, Zalacain M. Chan PF, et al. Among authors: holmes dj. J Bacteriol. 2003 Mar;185(6):2051-8. doi: 10.1128/JB.185.6.2051-2058.2003. J Bacteriol. 2003. PMID: 12618474 Free PMC article.

10

Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery.

Payne DJ, Warren PV, Holmes DJ, Ji Y, Lonsdale JT. Payne DJ, et al. Among authors: holmes dj. Drug Discov Today. 2001 May 1;6(10):537-544. doi: 10.1016/s1359-6446(01)01774-3. Drug Discov Today. 2001. PMID: 11369293

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