Deane R - Search Results

1

Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor.

Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, Zlokovic BV, Van Nostrand WE. Davis J, et al. Among authors: deane r. J Biol Chem. 2004 May 7;279(19):20296-306. doi: 10.1074/jbc.M312946200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985348 Free article.

2

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV. Deane R, et al. Neuron. 2004 Aug 5;43(3):333-44. doi: 10.1016/j.neuron.2004.07.017. Neuron. 2004. PMID: 15294142 Free article.

3

RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier.

Deane R, Wu Z, Zlokovic BV. Deane R, et al. Stroke. 2004 Nov;35(11 Suppl 1):2628-31. doi: 10.1161/01.STR.0000143452.85382.d1. Epub 2004 Sep 30. Stroke. 2004. PMID: 15459432

4

Neurovascular pathways and Alzheimer amyloid beta-peptide.

Zlokovic BV, Deane R, Sallstrom J, Chow N, Miano JM. Zlokovic BV, et al. Among authors: deane r. Brain Pathol. 2005 Jan;15(1):78-83. doi: 10.1111/j.1750-3639.2005.tb00103.x. Brain Pathol. 2005. PMID: 15779240 Free PMC article. Review.

5

Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease.

Deane R, Zlokovic BV. Deane R, et al. Curr Alzheimer Res. 2007 Apr;4(2):191-7. doi: 10.2174/156720507780362245. Curr Alzheimer Res. 2007. PMID: 17430246 Review.

6

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice.

LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV. LaRue B, et al. Among authors: deane r. J Neurosci Methods. 2004 Sep 30;138(1-2):233-42. doi: 10.1016/j.jneumeth.2004.04.026. J Neurosci Methods. 2004. PMID: 15325132

7

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.

Chow N, Bell RD, Deane R, Streb JW, Chen J, Brooks A, Van Nostrand W, Miano JM, Zlokovic BV. Chow N, et al. Among authors: deane r. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):823-8. doi: 10.1073/pnas.0608251104. Epub 2007 Jan 10. Proc Natl Acad Sci U S A. 2007. PMID: 17215356 Free PMC article.

8

Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity.

Guo H, Singh I, Wang Y, Deane R, Barrett T, Fernández JA, Chow N, Griffin JH, Zlokovic BV. Guo H, et al. Among authors: deane r. Eur J Neurosci. 2009 Mar;29(6):1119-30. doi: 10.1111/j.1460-9568.2009.06664.x. Eur J Neurosci. 2009. Retraction in: Eur J Neurosci. 2024 Nov;60(10):6588. doi: 10.1111/ejn.16587 PMID: 19302148 Free PMC article. Retracted.

9

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.

Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. Among authors: deane r. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.

10

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system.

Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV. Bell RD, et al. Among authors: deane r. J Cereb Blood Flow Metab. 2007 May;27(5):909-18. doi: 10.1038/sj.jcbfm.9600419. Epub 2006 Nov 1. J Cereb Blood Flow Metab. 2007. PMID: 17077814 Free PMC article.

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